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Can Lyme Disease Be Chronic

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What Is Late Lyme Disease

Does Chronic Lyme Disease Exist?

Lyme disease, also known as Lyme borreliosis, is caused by an infection with the bacteria Borrelia burgdorferi. This bacteria is disseminated through tick bites. Infected ticks usually bite small mammals, who do not develop any kind of infection from the bacteria. When humans are exposed to B. Burgdorferi from a tick bite, however, they can develop Lyme disease.

People who work outside or spend time in woodland areas, where there is greater potential for exposure to tick bites, are most at risk of infection.

Lyme disease is a condition which progresses in stages:

  • A person will initially develop early localized lyme disease, in which the bacteria have not yet spread through the body. At this stage, which generally has its onset days or weeks after the tick bite, a personâs symptoms will usually include a fever, fatigue, and a rash, called the Erythema Migrans rash, which has a distinctive bullsâ eye shape and affects around two thirds of people who develop Lyme disease. See this resource for more information on symptoms and treatment of early localized Lyme disease.
  • If Lyme disease is not diagnosed in either of these early stages, and is not treated effectively with antibiotics, the bacteria that cause LD can spread throughout the body from the site of the tick bite, resulting in late disseminated Lyme disease, or late lyme disease. The onset of symptoms and complications of late disseminated Lyme disease is usually around 6-36 months after the original infection.
  • How To Remove A Tick

    A tick must remain attached to the skin for at least 36 hours to spread Lyme disease. The best way of preventing Lyme disease is to remove a tick as soon as possible.

    The blacklegged tick that spreads disease-causing bacteria resembles a tiny spider. Young ticks are around the size of a poppy seed, while adult ticks are around the size of a sesame seed. Ticks of all ages are reddish-brown.

    Below are some steps for tick removal.

    • Step 1: Use fine-tipped tweezers to gently grasp the tick near its head or mouth. Avoid squeezing the tick.
    • Step 2: Using the tweezers, pull the tick carefully and steadily away from the skin. Avoid yanking or twisting the tick, as this could cause its mouthparts to remain in the skin.
    • Step 3: After removing the tick, dispose of it by putting it in some alcohol or flushing it down the toilet.
    • Step 4: Apply antiseptic to the tick bite.

    Do Dogs Recover From Lyme Disease

    Lyme disease in dogs is curable, however, this may depend on each case and at what stage of the disease the dog receives treatment during.

    In most cases, symptoms will begin to lessen after 3 days of treatment.

    When treating Lyme disease, its important to know that this illness is not always curable.

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    Who Should Get Testing

    Testing is usually indicated if a person has symptoms of Lyme disease and a known or possible exposure to ticks that can carry the Borrelia bacteria. However, because it takes time for antibodies to develop, the timing of testing is important to consider.

    Lyme disease symptoms depend on the extent of the bacterial infection. Three phases are used to describe the infection:

  • Early localized: In this initial phase, symptoms are normally found only near the tick bite. This early stage is called erythema migrans and involves a noticeable rash that typically develops within a few weeks after being bitten.
  • Early disseminated: In this phase, the bacteria move through the blood to affect other parts of the body and can cause general symptoms like fever, headaches, and pain. In some cases, the bacteria can affect the heart or nervous system.
  • Late disease: This phase occurs long after the initial tick bite and most often includes symptoms affecting the joints or nervous system.
  • It is important to understand these phases because testing is not equally valuable in each stage. With early localized disease and erythema migrans, blood testing is generally not helpful because antibodies have not had enough time to develop.

    Because of similar concerns about potential false positive results, random screening for Lyme disease in people without symptoms is not recommended even in areas that are known to have ticks that can carry the Borrelia bacteria.

    Does Heat Make Lyme Disease Worse

    Lyme Disease Support

    Some patients bodies have trouble regulating blood pressure and heart rate, and extreme temperatures can send those processes into distress. Common Lyme symptoms of dizziness, fatigue, and joint acheshard enough to deal with on a moderate dayare intensified in the heat of summer or the bitterness of winter.

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    Chronic Lyme: What Happens When Lyme Goes Untreated

    The Lyme community typically uses the term chronic Lyme disease to describe a range of physical, cognitive, and emotional symptoms that crop up after getting Lyme disease and persist for months to years after infection.

    The risk of chronic Lyme increases the longer a Lyme infection goes untreated or undertreated. In other words, patients are more likely to recover fully if their Lyme infection is detected and treated as early as possible after the discovery of a tick bite. This stage is usually marked by symptoms such as fevers, chills, muscle aches, and sometimes rashes.

    When left untreated or undertreated, however, Lyme disease can spread throughout the body and affect:

    • The central nervous system
    • Muscles and joints

    As Lymedisease.org points out, these symptoms can evolve, disappear, and reappear at different times.

    How Stephanie Got Answers

    About four years ago, Tait started to suspect she had Lyme disease. A family friend had Lyme, and Tait recognized some of her own symptoms appearing in her friend. She asked her doctor for an ELISA, an enzyme-linked immunosorbent assay, or a blood test thats typically the first way doctors test patients who may have Lyme disease. When she learned her insurance wouldnt cover the cost, she paid for the test out of pocket. It came back negative.

    Tait, however, wasnt convinced. She asked for another test, but she said the doctor refused. So she turned to a private lab for a second test, this one a Western Blot, which doctors typically turn to next, to verify a positive ELISA result. That test was positive for the Lyme antibodies.

    I sobbed, because there it was in my hands that I wasnt just jumping to conclusions, Tait said. I walked back into my doctors office and said, Here it is. They said, Well, we didnt do this test, so how do we know? I said, Youve got to be kidding me. I have a lab test!

    Tait started getting treatment at a private clinic in Idaho that specializes in treating Lyme disease, about a six-hour drive from where she lives.

    Lyme disease is typically treated with antibiotics, and when treated early, people with Lyme usually recover completely. Taits treatment plan included antibiotics, immunotherapy, various supplements as well as dietary changes. But because she had been sick for so long, some of her health problems were irreversible.

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    Is Lyme Disease Curable

    The tick-borne illness can be treated with antibiotics, and most people make a full recovery within weeks or months. So why is there so much confusion?

    In much of the country, spring and summer mean warmer weather and spending more time outdoors. Unfortunately, it also means that the ticks that carry Lyme disease bacteria may be out in full force, especially in wooded or grassy areas.

    About 30,000 cases of Lyme disease are reported each year to the U.S. Centers for Disease Control and Prevention, although experts estimate that 10 times that amount may actually be infected. Thats concerning, because if left untreated, Lyme disease can cause nerve damage, memory loss, dangerous inflammation around the heart, and other permanent health problems.

    But the good news is that Lyme disease is also very treatableespecially when its diagnosed soon after symptoms begin. Lyme disease is always curable, Daniel Kuritzkes, MD, chief of the Division of Infectious Diseases at Brigham and Womens Hospital in Boston, tells Health. The medications we have are very effective at getting rid of the infection. Heres what else you need to know.

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    Will You Develop Permanent Complications From Lyme Disease

    How Lyme Disease and Chronic Infections Can Lead to Cancer

    Nobody really knows. A lot of it depends on the Lyme infection specifics , individual physiology , and the specific treatment .

    One person might develop a very severe Borrelia infection and end up with zero permanent adverse effects after treatment whereas another person might develop a moderately-severe infection yet end up with permanent complications.

    People with short-term and/or less severe Lyme disease are probably more likely to have most or all symptoms fade after treatment.

    People with long-term and/or severe Lyme disease are probably more likely to experience some permanent complications that never go away after treatment is over.

    Note: Certain symptoms that one might initially suspect to be permanent may actually be reversible. For example, hyperalgesia and allodynia usually result from CNS sensitization .

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    Defining Patient Subgroups: Post

    Patients with persistent symptoms related to Lyme disease likely represent a heterogeneous population, which includes previously untreated patients, as well as those treated patients who remain symptomatic. As a result, some will manifest primarily patient-reported symptoms while others will present with symptoms in conjunction with objective, physical findings. This heterogeneity is further complicated by variation in terminology and the definitions used by different groups in the field.

    Figure 3. A schematic of clinical- and research-defined patient subgroups among those with persistent symptoms associated with Lyme disease . The size of each patient subgroup is not meant to represent actual population frequency, as prevalence data is extremely limited. IDSA, Infectious Diseases Society of America ILADS, International Lyme and Associated Diseases Society CLD-PT, Chronic Lyme Disease-Previously Treated CLD-U, Chronic Lyme Disease-Untreated IgG, Immunoglobulin G CFS, Chronic Fatigue Syndrome FM, Fibromyalgia.

    The Numbers On Chronic Lyme

    Because Lyme disease is commonly missed or misdiagnosed, statistics vary on how many Lyme patients go on to experience chronic symptoms. The following research nonetheless paints a basic picture of the problem.

    • An estimated 5-20% of patients may have chronic symptoms after getting Lyme disease, according to the Columbia University Irving Medical Center.
    • The treatment failure rate for chronic Lyme disease patients was estimated at 26-50% in 2004, compared to 16-39% for early Lyme patients, according to Lymedisease.org.
    • Up to 15-40% of late-stage Lyme patients develop neurological disorders, which are responsible for many common symptoms of chronic Lyme disease.

    Experts dont know for sure why some people experience persistent symptoms, even with treatment. However, some believe the Lyme infection may trigger an auto-immune response that manifests in the chronic symptoms detailed below.

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    Has Niaid Looked At The Potential Benefits Of Long

    Yes. NIAID has funded three placebo-controlled clinical trials on the efficacy of prolonged antibiotic therapy for treating PTLDS. The published results were subjected to rigorous statistical, editorial, and scientific peer review.

    These trials were designed to ensure that several key parameters were addressed:

    • The susceptibility of B.burgdorferi to the antibiotics used
    • The ability of the antibiotics to both cross the blood-brain barrier and access the central nervous system and to persist at effective levels throughout the course of therapy
    • The ability of the antibiotics to kill bacteria living both outside and inside mammalian cells
    • The safety and welfare of patients enrolled in the trials

    The first clinical trial, which included two multicenter studies, provided no evidence that extended antibiotic treatment is beneficial. In those studies, physicians examined long-term antibiotic therapy in patients with a well-documented history of previous Lyme disease but who reported persistent pain, fatigue, impaired cognitive function, or unexplained numbness. Those symptoms are common among people reporting PTLDS. Patients were treated with 30 days of an intravenous antibiotic followed by 60 days of an oral antibiotic.

    In 2016, a clinical trial conducted in the Netherlands also concluded that in patients with persistent symptoms attributed to Lyme disease, longer term treatment with antibiotics did not provide additional benefits compared with shorter term regimens.

    Proof That Chronic Lyme Disease Exists

    Chronic Lyme Disease: Symptoms, Causes and CoInfections

    Daniel J. Cameron

    1Department of Medicine, Northern Westchester Hospital, Mt. Kisco, NY 10549, USA

    Academic Editor:

    Abstract

    The evidence continues to mount that Chronic Lyme Disease exists and must be addressed by the medical community if solutions are to be found. Four National Institutes of Health trials validated the existence and severity of CLD. Despite the evidence, there are physicians who continue to deny the existence and severity of CLD, which can hinder efforts to find a solution. Recognizing CLD could facilitate efforts to avoid diagnostic delays of two years and durations of illness of 4.7 to 9 years described in the NIH trials. The risk to society of emerging antibiotic-resistant organisms should be weighed against the societal risks associated with failing to treat an emerging population saddled with CLD. The mixed long-term outcome in children could also be examined. Once we accept the evidence that CLD exists, the medical community should be able to find solutions. Medical professionals should be encouraged to examine whether: innovative treatments for early LD might prevent CLD, early diagnosis of CLD might result in better treatment outcomes, and more effective treatment regimens can be developed for CLD patients who have had prolonged illness and an associated poor quality of life.

    References

  • H. M. Feder Jr. and D. L. Whitaker, Misdiagnosis of erythema migrans, American Journal of Medicine, vol. 99, no. 4, pp. 412419, 1995. View at: Publisher Site |
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    Do You Ever Fully Recover From Lyme Disease

    Although most cases of Lyme disease can be cured with a 2- to 4-week course of oral antibiotics, patients can sometimes have symptoms of pain, fatigue, or difficulty thinking that last for more than 6 months after they finish treatment. This condition is called Post-Treatment Lyme Disease Syndrome .

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    Is There A Lyme Disease Test Kit

    Blood collection kits are available for at-home Lyme disease testing. Lyme disease test kits can cost as less as $20 and as much as $100 or more. Using a Lyme disease test kit is as simple as pricking your finger and smearing or collecting the blood onto the kit for testing.

    However, testing for Lyme disease in a more controlled environment such as a lab or clinic is preferable as qualified healthcare professionals are likely to perform a more reliable test.

  • Center for Disease Control and Prevention . Data and surveillance. Retrieved from
  • Eugene D. S. . Lyme disease. N Engl J Med 2014 370:1724-1731. Retrieved from
  • Zeller J. L. . Lyme disease. JAMA. 2007 297:2664. Retrieved from
  • Center for Disease Control and Prevention . Diagnosis and testing. Retrieved from
  • Waddell L. A., et al. . The accuracy of diagnostic tests for Lyme disease in humans, a systematic review and meta-analysis of North American research. PLoS One. 2016 11: e0168613. Retrieved from

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    Supplements For Chronic Lyme Disease

    You may want to focus on a combination of neuroprotective, neuro-restorative, immunomodulatory, and/or anti-inflammatory supplements after Lyme disease.

    These are supplements that Id consider taking if treated for Lyme disease.

    Examples of supplements that might help with the aftermath of Lyme:

    Disclosure: These are affiliate links and help support the site. Cost is exact same.

    • Note: Always consult a medical doctor to verify that supplements are safe given your current medical status and medication regimen.
    • Note: I am just listing some that might help some individuals. Do NOT combine without verifying safety. Each has specific uses.

    Lyme Disease Warrants Additional Research

    Can You Ever Be Truly Cured of Lyme Disease?

    Included below are some aspects of Lyme disease that I think warrant further research.

    Lyme disease vaccines: There are no approved vaccines for the prevention of Lyme disease in the United States. Many believe that vaccines warrant development due to the significant healthcare costs and productivity losses resulting from Lyme disease.

    : New compounds for the treatment of Lyme disease are warranted. Perhaps newer antimicrobials that are better able to target Borrelia bacteria will eliminate Borrelia and all persister material during treatment.

    • Azlocillin
    • Hygromycin A

    Biomarkers of chronic Lyme: Are there any commonalities in terms of biomarkers among individuals with Post-Lyme Disease Treatment Syndrome ? These may warrant additional investigation.

    Persister material: Research indicates that B. burgdorferi can form persister organisms due to both antibiotic pressure and stationary phase growth.

    • Does the amount or type of persister material correlate with severity of chronic Lyme symptoms?
    • Are there any potential methods to eliminate the persister material?
    • Does eliminating persister material result in symptomatic improvement or curative effect?

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    Six Years After Tick Bite Its Markand The Illnessstill Show

    You see that little spot on my calf? You wouldnt think that a small bite like this would change someones life, turn it upside down, crush their goals and dreams, shake them to their core, causing immense pain and profound fatigue along with a multitude of other symptoms and issues.

    That bite also caused a secondary neurological disorder which affects my heart and all body systems , as well as a brain lesion. That bite is from a tick. Yes thats a tick bite from six years ago! Out of the hundreds of people with Lyme disease that I have met, only one other had a re-appearing bite years after she was bitten. This is not very common, but it does show how resilient and chronic this bacteria can be.

    I remember the day as if it were yesterday. We were at a local creek, and the tick was only attached for a few hours. My husband saw the tick, as well as my parents, and my father removed the tick for me.

    A few weeks later I developed flu-like symptoms and a rash . Because my case was not a textbook diagnosis, I was sent away without even being prescribed precautionary antibiotics.

    Also, I was told that we did not have Lyme disease in Georgia so the doctor refused to order a Lyme disease test. Pretty tragic that the urgent care doctors decision and lack of knowledge has affected my entire life six years later.

    We need recognition, we need accurate testing, we need Lyme-literate doctors, we need understanding, we need awareness, we need a cure!

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