How Is Lyme Disease Spread
Lyme disease is spread by the bite of an infected black-legged tick. The tick usually must be attached to a person for at least 24 hours before it can spread the germ. Black-legged ticks in Massachusetts can also carry the germs that cause babesiosis and human granulocytic anaplasmosis). These ticks are capable of spreading more than one type of germ in a single bite.
A Targeted Lyme Disease Treatment
But back to the optimism mentioned at the start of this article: During a recent study, a team under Kim Lewis at Northeastern University found that a compound called hygromycin A is completely harmless to animals and has little effect on most bacteria except so-called spirochete bacteria, named for their spiral shape. For those, it is deadly. And Borrelia burgdorferi, the pathogen that causes Lyme disease, belongs to just this group.
Hygromycin A is an antimicrobial agent found in soil. The substance was originally discovered in 1953. At the time, however, scientists dismissed it as ineffective, probably because it seemed too weak to fight normal pathogens. But Lewis considers it exceptionally effective against spirochetes.
Lewis team discovered the efficacy of hygromycin A while screening microorganisms in soil for antimicrobial compounds. We set out to find such a compound that would selectively kill Borreliella burgdorferi , placing a bet, if you will, that Mother Nature had bothered to evolve a compound to selectively take out spirochetes that live in the soils, Lewis says.
And indeed, Mother Nature has done exactly that.
The researchers have already licensed the compound to Flightpath, a biotech company specializing in Lyme disease, to conduct development studies and advance production of this treatment.
How Lyme Antibody Testing Works
Antibody testing for Lyme disease requires two different tests to establish a positive result. If either the first tier test or the second tier test is negative, the test result is negative overall.
But in the event of a negative result, Dr. Adriana Marques of the NIH states:
For patients with signs or symptoms consistent with Lyme disease for less than or equal to 30 days, the provider may treat the patient and follow up with testing of convalescent-phase serum.
The first tier of the two-tiered testing system is an Enzyme Immunoassay .
The second tier of the well-established Standard Two-Tiered Testing involves a Western Blot test, which can be complicated to understand. The Western Blot is also called an immunoblot or a line blot.
The Western Blot test typically reports two types of antibodies that may be indicative of a Lyme infection: IgM and IgG.
According to the CDC, Positive IgM results should be disregarded if the patient has been ill for more than 30 days.
According to a consensus of experts, including representatives of the American Academy of Pediatrics, American Academy of Neurology, American College of Rheumatology, and Infectious Diseases Society of America:
Immunoglobulin G seronegativity in an untreated patient with months to years of symptoms essentially rules out the diagnosis of Lyme disease, barring laboratory error or a rare humoral immunodeficiency state.
Also Check: How To Cure Lyme Disease In Dogs
How Will Pregnancy Affect Treatment For Lyme Disease
Early treatment of Lyme disease during pregnancy is important. Thats because if Lyme disease is untreated, it can affect the placenta. According to the CDC , the transmission of Lyme disease from mother to fetus is possible, though rare.
For pregnant people, treatment includes a round of antibiotics. Certain treatments for Lyme disease may not be used, as they can affect the fetus. If you suspect that you have Lyme disease, talk with a healthcare professional immediately.
A Reasonable Approach To Post
If you are being treated for PTLD, there is no magic bullet to treat this problem, but here are some important steps to consider:
- Choose a doctor you trust and who can work closely with you.
- If your doctor agrees to start antibiotics for several months, make sure you talk about the risks and cost, as this can be dangerous and expensive.
- Make sure not to rely solely on antibiotics. The evidence for a benefit from antibiotics is weak, and we rely mostly on physicians clinical experience and interest in the disease to design a personalized therapeutic plan. For some, a more holistic approach may be the way to go.
- If you try supplements, ask about their source and purity, as they are not FDA-regulated.
- Consider looking for services in medical school hospitals or clinics where they may have programs with ongoing research on how to diagnose and treat Lyme.
Read Also: How Did Lyme Disease Start
Signs Of Lyme Disease That Appear On Your Skin
Signs of Lyme disease
If you see a rash or another sign of Lyme disease on your skin, see your primary doctor right away. When caught early and treated, Lyme disease can be cured with antibiotics and most people recover fully.
Lyme disease is caused by a bite from a black-legged tick. If you are bitten by this tick and develop Lyme disease, you may see a bulls-eye rash. Its a common sign of Lyme disease, but its not the only sign.
Lyme disease occurs in stages. Heres what you may see on your skin during each stage.
Hyperbaric Oxygen Therapy For Lyme Disease
Hyperbaric oxygen therapy involves exposure to 100 percent oxygen at a high pressure. Its often in a room called a hyperbaric oxygen chamber to promote wound healing.
There isnt much research about the effectiveness of hyperbaric oxygen therapy for Lyme disease. But a 2014 case study from Taiwan reports that it treated Lyme disease in a person who hadnt responded to antibiotics. Still, more large-scale studies are needed to understand whether its an effective treatment.
You May Like: Can You Prevent Lyme Disease After A Tick Bite
Read Also: Do Rheumatologists Treat Lyme Disease
Cdc Supports The Development Of New Tests
New tests may be developed as alternatives to one or both steps of the two-step process. Before CDC will recommend new tests, they must be cleared by the Food and Drug Administration . For more details, see: Recommendations for Test Performance and Interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease.
Prognosis Of Lyme Disease
People treated with antibiotics in the early stages of Lyme disease usually make a full recovery. Without treatment there can be complications that involve the joints, heart and nervous system, but these symptoms can still go away with treatment.
Although it is rare, some people develop whats called post-Lyme disease syndrome. Those individuals still have symptoms of Lyme Disease that interfere with their life even after theyve been treated, according to MedlinePlus.
Also Check: What Size Ticks Carry Lyme Disease
Can Lyme Disease Be Prevented
To prevent Lyme disease, you should lower your risk of getting a tick bite:
- Avoid areas where ticks live, such as grassy, brushy, or wooded areas. If you are hiking, walk in the center of the trail to avoid brush and grass.
- Use an insect repellent with DEET
- Treat your clothing and gear with a repellant containing 0.5% permethrin
- Wear light-colored protective clothing, so you can easily see any ticks that get on you
- Wear a long-sleeve shirt and long pants. Also tuck your shirt into your pants and your pant legs into your socks.
- Check yourself, your children, and your pets daily for ticks. Carefully remove any ticks you find.
- Take a shower and wash and dry your clothes at high temperatures after being outdoors
Centers for Disease Control and Prevention
What Can I Do To Lower My Chances Of Getting Lyme Disease Or Any Other Disease From Ticks
Prevention begins with you! Take steps to reduce your chances of being bitten by any tick. Ticks are most active during warm weather, generally late spring through fall. However, ticks can be out any time that temperatures are above freezing. Ticks cling to vegetation and are most numerous in brushy, wooded or grassy habitats. When you are outside in an area likely to have ticks , follow these simple steps to protect yourself and your loved ones:
You May Like: Signs And Symptoms Of Lyme Disease In Child
How Do I Remove A Tick From My Dog
Check your pet immediately after it has been in a tick-infected area. The deer tick is a small tick and only about pinhead size in juvenile stage, but is a little more obvious in the adult phase and after feeding. If you find a tick moving on your pet, the tick has not fed. Remove the tick promptly and place it in rubbing alcohol or crush it between two solid surfaces. If you find a tick attached to your pet, grasp the tick with fine tweezers or your finger nails near the dog’s skin and firmly pull it straight out. There are also tools available called Tick Twister® or Tick Key® which can be useful. However, take care to use them cautiously as twisting or jerking the tick may cause the mouth parts to break off and remain in the skin. See your veterinarian if you are unsure or unable to remove the tick from your dog.
Make sure you protect your fingers from exposure by using a tissue or a disposable glove.You may need another person to help restrain your dog. Removing the tick quickly is important since the disease does not appear to be transmitted until the tick has fed for approximately 12 hours. If you crush the tick, do not get the tick’s contents, including blood, on your skin.
Note: The bacterium that causes Lyme disease can pass through a wound or cut in your skin.
What If Your Lyme Disease Test Is Positive
Its important to note that a positive result doesnt mean you have a diagnosis of Lyme disease. The tests will show that antibodies are present in your blood, but a doctor will need to order another type of test before you get an official diagnosis.
If someone gets a positive at-home test, definitely see your doctor, says Puja Uppal, DO, a board certified family medicine physician and the chief medical officer at Think Healthy.
A doctor will likely order both an enzyme-linked immunosorbent assay and a Western blot test, which check for antibodies specific to Borrelia burgdorferi. They will consider the results of both these tests, along with your symptoms, to make an accurate diagnosis.
Don’t Miss: Doxycycline Monohydrate For Lyme Disease
How To Spot And Remove Ticks
Once youve come in from outside, one of the best ways to check yourself for ticks is to take a shower and bath.
Other than that, do your best to check your clothes, especially the folds of your clothes, knowing that ticks can be very small and hard to spot. Running your hands through your hair is also a good idea.
When A Lyme Diagnosis Is Tricky
There are several reasons it can be hard to diagnose Lyme disease.
Tests are less accurate for a short period of time after you first become infected. Thats because Lyme tests look for proteins created by your immune system to help you fight off infection , rather than for the infection itself, and it can take a few weeks for your body to make enough antibodies to cause a positive test.
The only sure sign of Lyme disease is an erythema migrans rash, which often has a bullseye shape. But up to 30% of people who get Lyme disease never get a rash. It is also possible that a person may not notice a rash before it goes away.
Symptoms of Lyme disease like fever and body aches can also be caused by other illnesses. This may result in Lyme diagnoses being missed because symptoms are attributed to another illness.
Using todays tests, it is difficult to distinguish between an old Lyme disease infection and a new one.
Thats why Lyme disease cases may be missed, and as many as 40% of Lyme disease cases are not diagnosed until a later stage of the disease. By that time, Lyme disease is harder to treat, and long-term complications are more likely, so an early, accurate diagnosis is very important.
Recommended Reading: Pizza Delivery Old Lyme Ct
Signs And Symptoms Of Untreated Lyme Disease
Seek medical attention if you observe any of these symptoms and have had a tick bite, live in an area known for Lyme disease, or have recently traveled to an area where Lyme disease occurs.
Untreated Lyme disease can produce a wide range of symptoms, depending on the stage of infection. These include fever, rash, facial paralysis, and arthritis.
The appearance of the erythema migrans rash can vary widely.
- Fever, chills, headache, fatigue, muscle and joint aches, and swollen lymph nodes may occur in the absence of rash
- Erythema migrans rash :
- Occurs in approximately 70 to 80 percent of infected persons
- Begins at the site of a tick bite after a delay of 3 to 30 days
- Expands gradually over several days reaching up to 12 inches or more across
- May feel warm to the touch but is rarely itchy or painful
- Sometimes clears as it enlarges, resulting in a target or bulls-eye appearance
- May appear on any area of the body
- Does not always appear as a classic erythema migrans rash
- Severe headaches and neck stiffness
- Additional EM rashes on other areas of the body
- Arthritis with severe joint pain and swelling, particularly the knees and other large joints.
- Intermittent pain in tendons, muscles, joints, and bones
- Heart palpitations or an irregular heart beat
- Episodes of dizziness or shortness of breath
- Inflammation of the brain and spinal cord
Links with this icon indicate that you are leaving the CDC website.
The Role Of Lyme Disease Tests
The purpose of the most common type of Lyme disease testing is to determine whether you have developed antibodies as a result of past exposure to the Borrelia bacteria that cause Lyme disease. Antibodies are proteins created by the immune system that target specific threats like bacteria and viruses.
Blood testing alone cannot determine whether you have Lyme disease. Instead, testing can provide helpful information that your doctor can consider along with other factors, such as any symptoms youve had and whether youve been exposed to ticks that can carry Borrelia, to determine if a diagnosis of Lyme disease is appropriate.
Beyond blood testing, it is possible to analyze fluid from the central nervous system for signs of the Borrelia bacteria.
Read Also: How Does Someone Get Lyme Disease
When Should I Get Checked For Lyme Disease
Generally, it is best to get tested for Lyme disease if you live where ticks are common or have recently visited such areas. Most certainly, you should get tested if you suspect that a tick has bitten you. It is important to talk to your doctor if you think you have any of the following early Lyme disease symptoms:
- A rash resembling a bulls eye on the spot where youve been bitten
Other symptoms dont show up immediately. Sometimes, it takes up to a few weeks or months after the tick bite to notice the following:
- Swelling on the joints or severe joint pain
- Tingling in the feet and hands
- Shortness of breath
While it is okay get checked early, Lyme disease test results numbers are more authentic a few weeks after youve been bitten by a carrier-tick. Your body would have developed antibodies within that period, and that can make it easier to detect the disease.
Recommended Reading: What Are The Side Effects Of Lyme Disease In Humans
What Are The Clinical Signs Of Lyme Disease
Some people with Lyme disease develop a characteristic bull’s-eye rash at the site of the bite within three to thirty days. If this occurs, the disease can be easily diagnosed at an early stage.
However, signs of Lyme disease are more difficult to detect in animals than in people. The characteristic rash does not develop in dogs or cats. In fact, Lyme disease is practically unheard of in cats.
“Affected dogs have been described as if they were walking on eggshells.”
Many dogs affected with Lyme disease are taken to a veterinarian because they seem to be experiencing generalized pain and have stopped eating. Affected dogs have been described as if they were walking on eggshells. Often these pets have high fevers. Dogs may also begin limping. This painful lameness often appears suddenly and may shift from one leg to another. If untreated, it may eventually disappear, only to recur weeks or months later.
Some pets are infected with the Lyme disease organism for over a year before they finally show symptoms. By this time, the disease may be widespread throughout the body. Non-specific signs which may indicate that Lyme disease is affecting the kidneys include vomiting, lethargy, anorexia , and weight loss. The kidney form of the disease is less common, but often fatal.
Also Check: Are Lyme Disease Tests Accurate
Prevention Of Lyme Disease
There currently isnt a vaccine to protect against Lyme disease. Per the FDA, the following precautions can help reduce your chances of getting a tick bite:
- Avoid woody, brushy and grassy areas, especially in May, June, and July.
- Wear light-colored clothes so that you can spot a tick if it gets on you.
- Wear long pants and long-sleeved shirts and shoes that cover your whole foot
- Tuck your pant legs into socks or shoes and tuck your shirts into your pants.
- Wear a hat to protect your head.
- Spray insect repellant containing DEET on clothes and areas of uncovered skin.
- If youre on a trail, walk in the center to avoid brush and grass.
- Take off your clothes right away when you come in from the outdoors and wash and dry them at high temperatures.
- Carefully check your body and head for ticks after outdoor activities.