Does Heat Make Lyme Disease Worse
Some patients’ bodies have trouble regulating blood pressure and heart rate, and extreme temperatures can send those processes into distress. Common Lyme symptoms of dizziness, fatigue, and joint acheshard enough to deal with on a moderate dayare intensified in the heat of summer or the bitterness of winter.
Potential Treatment For Lyme Disease Kills Bacteria That May Cause Lingering Symptoms Study Finds
Screening thousands of drugs, Stanford scientists determined that in mice, azlocillin, an antibiotic approved by the Food and Drug Administration, eliminated the bacteria that causes Lyme disease.
Deer ticks are vectors of Borrelia burgdorferi, the bacteria that causes Lyme disease.Scott Bauer/USDA Agricultural Research Service
For decades, the routine treatment for Lyme disease has been standard antibiotics, which usually kill off the infection. But for up to 20% of people with the tick-borne illness, the antibiotics dont work, and lingering symptoms of muscle pain, fatigue and cognitive impairment can continue for years sometimes indefinitely.
A new Stanford Medicine study in lab dishes and mice provides evidence that the drug azlocillin completely kills off the disease-causing bacteria Borrelia burgdorferi at the onset of the illness. The study suggests it could also be effective for treating patients infected with drug-tolerant bacteria that may cause lingering symptoms.
This compound is just amazing, said Jayakumar Rajadas, PhD, assistant professor of medicine and director of the Biomaterials and Advanced Drug Delivery Laboratory at the Stanford School of Medicine. It clears the infection without a lot of side effects. We are hoping to repurpose it as an oral treatment for Lyme disease. Rajadas is the senior author of the study, which was published online March 2 in Scientific Reports. The lead author is research associate Venkata Raveendra Pothineni, PhD.
How Much Does It Cost To Treat A Dog With Lyme Disease
A four-week antibiotic course might cost around $800, plus the cost of the diagnostic blood tests may approximately be an additional $80 to $200 depending on the type of tests, in addition to the vet consultation fees. Add in the cost of your dogs prescription medications, and that can be costly for many pet parents.
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Understanding The Acute Inflammatory Response
Suppose youre walking barefoot in the yard one summer day and accidentally step on a sharp piece of glass hidden in the grass. Pain alerts you to the injury and you stop to assess the situation. If the wound isnt deep, youre up to date on your tetanus vaccination, and a rinse in the sink reveals no foreign objects in the wound, you place a bandage over the area, and youre back on your way.
Swelling occurs because blood vessels dilate to allow an influx of WBCs and flush the area with fluid. Macrophages and arriving WBCs engulf debris, foreign matter, and microbes that have entered through the open wound, and destroy the material with potent free radicals and hypochlorous acid. Its a noxious process that causes collateral damage to normal cells, but its part of the healing process.
Once the injury is contained and the mess is cleaned up, WBCs migrate out of the area. Surviving cells repair damage from the injury and the inflammatory process itself. Gradually evidence of the injury disappears like nothing had ever happened.
What Tests Are Used To Diagnose B Mayonii
Your healthcare provider may order a blood test to look for infection. Limited available information suggests that patients with B. mayonii infection develop antibodies that are similar to those of patients infected with B. burgdorferi. Therefore, Lyme disease serologic testing may help in diagnosing patients with B. mayonii. In some cases, B. mayonii bacteria may also be seen on a blood smear. Infection with B. mayonii can be specifically identified by Lyme disease molecular tests at Mayo Clinic. Lyme disease, including infection with B. mayonii, can be diagnosed without testing when patients have signs and symptoms consistent with Lyme disease and a history of possible exposure to blacklegged ticks.
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How Is Lyme Disease Diagnosed
Lyme disease is usually diagnosed via a blood test called an ELISA, or an enzyme-linked immunosorbent assay, explains Dr. Ormond. It can detect antibodies to B. burgdorferi, the bacteria that causes Lyme disease.
Less often, a doctor might test someones cerebrospinal fluid for antibodies via a lumbar puncture . This is usually done if a patient is experiencing symptoms that indicate their central nervous system has been affected, continues Dr. Ormond.
When Will A Lyme Disease Test Be Available
Ma’ayan said a test could be on the market in one to two years.
“It’s pretty exciting for me because most of the research that we do is very basic, so we don’t see a direct link to affecting patient lives right away,” Ma’ayan said. “And this is one of those rare cases where we do see a direct link.”
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Can Lyme Disease Be Prevented Or Avoided
The best way to prevent Lyme disease is to avoid being bitten by ticks. When you are outdoors, follow these guidelines:
- Avoid areas that are wooded, brushy, or have tall grass.
- Walk in the center of trails.
- Use an insect repellent with at least 20% DEET. It can be put on clothing or sparingly on the skin. Dont apply it to the face or hands of children.
- Treat clothing, tents, or other gear with repellents containing 0.5% permethrin.
- Wear light-colored clothing. This makes it easier to see and remove ticks from your clothes.
- Wear a long-sleeved shirt and long pants. Tuck your pant legs into your socks or boots for added protection.
After you get home, check everything and everyone for ticks.
- Bathe or shower as soon as you can to wash off any ticks that have not attached to you.
- Check your entire body for ticks. Use a mirror for places you cant see. Check your children and your pets. Common tick locations include the back of the knees, groin area, underarms, ears, scalp, and the back of the neck.
- Check any gear you used, including coats, backpacks, or tents.
Tumble dry clothes or blankets on high heat in the dryer for 10 to 15 minutes. This should kill any ticks. If clothes are dirty, wash them in hot water and dry on high heat for 60 minutes.
Diagnosing Lyme Disease In Dogs
You will need to provide a thorough history of your dog’s health to give your veterinarian clues as to which organs are being affected.
Clinical diagnosis of Lyme disease is usually confirmed with a positive blood test for Lyme along with the clinical signs associated with Lyme disease.
Its important to note that tests can take 4-6 weeks to show up as positive after exposure, which is why veterinarians will use a combination of diagnostics to diagnose your dog:
- Blood chemistry tests
- X-rays and tests specific to diagnosing Lyme disease
- Fluid from the affected joints may also be drawn for analysis
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How To Remove A Tick
A tick must remain attached to the skin for at least 36 hours to spread Lyme disease. The best way of preventing Lyme disease is to remove a tick as soon as possible.
The blacklegged tick that spreads disease-causing bacteria resembles a tiny spider. Young ticks are around the size of a poppy seed, while adult ticks are around the size of a sesame seed. Ticks of all ages are reddish-brown.
Below are some steps for tick removal.
- Step 1: Use fine-tipped tweezers to gently grasp the tick near its head or mouth. Avoid squeezing the tick.
- Step 2: Using the tweezers, pull the tick carefully and steadily away from the skin. Avoid yanking or twisting the tick, as this could cause its mouthparts to remain in the skin.
- Step 3: After removing the tick, dispose of it by putting it in some alcohol or flushing it down the toilet.
- Step 4: Apply antiseptic to the tick bite.
What To Expect At Home
Home care for dogs with Lyme disease is relatively straightforward. Doxycycline is usually given by mouth twice daily for at least 30 days. Improvement in the dogs symptoms should be noted within 24-48 hours. If the dogs condition fails to improve in 72 hours or worsens at any time, call your veterinarian.
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Stage : Early Localized Lyme Disease
Stage 1 or early localized Lyme disease occurs 128 days following a tick bite.
Some people with stage one Lyme disease do not experience any symptoms. If symptoms do occur, they may include the following:
- a skin rash that may or may not resemble a bulls-eye
- flu-like illness, including chills and a fever
- swollen lymph nodes
Which Areas Are More Likely To Have It
The tick that causes Lyme disease has been moving from the Northeast and upper Midwest into the Southern and Western U.S., Mexico, and Canada. Cases in California and Florida are on the rise. After a drop between 2017 and 2018, the numbers jumped a little bit in 2019.
But most Lyme cases in 2019 were in 15 states: Connecticut, Delaware, Maine, Maryland, Massachusetts, Minnesota, New Hampshire, New
Jersey, New York, Pennsylvania, Rhode Island, Vermont, Virginia, West Virginia, and Wisconsin. Washington, DC, is also a hotspot.
In 2019, Pennsylvania had the most Lyme infections, with 6,763. New York was next, with 2,847 cases.
In the Southern U.S., where itâs hotter, ticks stay under leaves so they don’t dry out. This means people donât get Lyme from Southern ticks very often because they don’t usually come out to bite.
Even though people only report about 30,000 cases of Lyme infection in the U.S. each year, there are actually around 476,000 a year. The same tick also can spread other diseases, including babesiosis, anaplasmosis, and Powassan virus. Those diseases are also on the rise in the U.S.
Whoâs likeliest to get Lyme disease?
Boys up to age 15 and men between the ages of 40 and 60 are the most likely to get Lyme disease. Thatâs because they tend to play outside and go camping, hunting, and hiking.
Why are there more ticks now than there used to be?
There are several reasons why Lyme is spreading. Some of these are:
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What Exactly Is Lyme Disease
Lyme disease usually starts with a rash that looks like a bullseye. Unfortunately, only around 50% of people get this classic Lyme disease rash. It may not be itchy, and it can show up anywhere on the body. There can be lots of different symptoms for Lyme Disease, but they commonly include extreme fatigue, headache, and jaw, neck, joint, bone or back pain. People who have Lymes generally feel extremely achy, sore and tired. Lyme disease is a multi-system disease meaning it affects a lot of different systems of the body. It also starts out as acute Lyme disease, but can turn chronic over time.
Its also important to know that Lyme disease can only be diagnosed by a physician. To get a firm diagnosis for Lyme disease, there are tests available, but some are more accurate than others. Direct microscopy is the preferred method for holistic practitioners according to Dr. Josh Axes site.
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Which Is More Effective Heat Or Red Infrared Light
Heat, whether it comes from a traditional or infrared sauna, is both a stimulating and destructive force. Heat causes additional stress to the body.
While the stress is temporary and the stress can lead to accelerating healing, the heat itself can cause damage when not used with caution. Both heat and red light can help Lyme Disease sufferers.
If you are choosing between them, you will probably get more powerful and lasting results with light therapy.
Light is a stimulating force that does not stress the body but rather, promotes healthy cell functioning, without any known side effects.
Red light therapy reduces inflammation and promotes healing from within.
It does this by:
- Stimulating mitochondrial activity
- Boosting production of stem cells, which are non-specialized cells that have the ability to develop into many different cell types including brain cells, muscle, and other soft tissue
- Promoting liver regeneration
- Red light also eases the symptoms of Lyme disease including Lyme arthritis, a painful and debilitating condition that results from inflammation of the joints, usually the knees.
To date, this Lyme arthritis study is the only study specially conducted on the effects of red light therapy on Lyme disease.
But given the broad range of therapeutic benefits, and the vast number of conditions that red light therapy is known to effectively help, it is reasonable to conclude that it could help you if you suffer from Lyme disease.
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Questions To Ask Your Doctor
- I found a tick embedded in my skin, but I cant get it out. What should I do?
- Ive been bitten by a tick. Do I need to be seen?
- Do I need a blood test to confirm Lyme disease?
- Which antibiotic is best for me?
- How long will I have to take the antibiotic?
- What tick or insect repellent should I use for me or my child?
- How long will the symptoms last?
- What should I do if I still dont feel well a long time after I was bitten?
Does Lyme Disease Go Away On Its Own
Its certainly possible for people to get Lyme disease and to clear the infection on their own, without treatment, says Dr. Kuritzkes. But its better to be treated, because some of the complicationslike arthritis and myocarditis and damage to the central nervous systemcan be very serious.
The type of bacteria that causes Lyme disease is in the same general family as the type that causes syphilis, Dr. Kuritzkes explains. That doesnt mean anything similar in terms of transmission, but syphilis has several different phases, with primary and secondary and tertiary symptoms, he says. The infection can hide out in the body for a long time and can cause problems down the road if its not treated.
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Q: Once Diagnosed How Should You Treat Lyme Disease
Research over the last three decades suggests that Lyme bacteria have multiple ways of evading the human immune system and that treating acute Lyme with 21 days of antibiotics fails approximately a third of patients.
For that reason, I treat in two phases. For early Lyme, I treat with four weeks of doxycycline, amoxicillin, or cefuroxime antibiotics.
I follow this up with four more weeks of drugs that prevent and eradicate persister forms of the bacteria. The persisters are drug-tolerant and can revert to an active infection once the antibiotics are stopped.
I aggressively treat late-Lyme patients who have severe degenerative neurologic or rheumatologic cases. As noted above, the very sick patients frequently have a mixture of tick-borne infections.
For these patients, I choose a combination of oral or, when needed, intravenous antibiotics that target the pathogens known to be present.
One Lyme Disease Diet
Its time to tighten the diet. Dial it in. Get strict. This doesnt mean you wont enjoy food it means its time to learn to enjoy salads! Make a salad every day, using at least ten different vegetables and at least five different herbs and spices. Variety is key, and be sure to mix it up, but always include garlic, turmeric, pepper, healthy fats like avocado, flax, and coconut oil, and get organic, fresh vegetables whenever possible.
Fruit is great to consume with this diet, but every time fruit is eaten, SF722 or another powerful fungal fighter needs to be taken with it.
Juicing is a common problem for us health nuts. Sweet juice is a refined sugar, even fresh squeezed organic orange juice. Beets, carrots, and all fruits , feed fungal infections, bacteria, and promote viruses. Juicing is fine, when done right. Juice regularly, but instead of those sweet juices, try ginger and turmeric shots . On the other hand, youre not likely to have much room for juicing because you will be drinking a lot of cranberry, stevia lemonade.
Every day, make a gallon of cranberry lemonade sweetened with stevia, and a very large salad . Obviously your size should be taken into consideration, dont kill yourself trying to drink a gallon a day if you only weigh 80 pounds, but for most people a gallon of water a day will do them a world of good.
Absolutely no alcohol is allowed on this diet save what little bit is in some of the recommended tinctures.
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Arthritis Caused By Lyme Disease
There are many causes for arthritis, and your veterinarian will focus on differentiating arthritis initiated by Lyme disease from other inflammatory arthritic disorders, such as trauma and degenerative joint disease.
Immune-mediated diseases will also be considered as a possible cause of the symptoms. X-rays of the painful joints will allow your doctor to examine the bones for abnormalities.
Can You Have Lyme Disease Without Knowing
The Lyme test came back positive. Greene is one of many people who don’t notice early signs of Lyme disease, brush off the symptoms, or whose medical providers missed the symptoms, which often include fever, headache, fatigue, and a bull’s-eye skin rash called erythema migrans, considered the hallmark of the disease.
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Hunting For Alternative Drug
Frustrated by the lack of treatment options for Lyme disease patients with lingering symptoms, Rajadas and his team began hunting for a better alternative in 2011. In 2016, they published a study in Drug Design, Development and Therapy that listed 20 chemical compounds, from about 4,000, that were most effective at killing the infection in mice. All 20 had been approved by the Food and Drug Administration for various uses. One, for instance, is used to treat alcohol abuse disorder.
In this most recent study, azlocillin, one of the top-20 contenders, was shown to eclipse a total of 7,450 compounds because it is more effective in killing B. burgdorferi and causes fewer side effects. Lyme disease affects more than 300,000 people annually, according to the Centers for Disease Control and Prevention. It can affect various organs, including the brain, skin, heart, joints and nervous system, and cause heart problems and arthritis if untreated. Symptoms include fever, headaches, chills, and muscle and joint pain.
Traditional antibiotics, such as doxycycline, are effective as an early course of treatment for the infection in the majority of patients, but it remains unclear why these drugs fail to treat 10% to 20% of patients, Rajadas said.
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