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How To Treat Lyme Co Infections

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Ticks Harbor Multiple Pathogens

Recover from Lyme Disease & Co-Infections

According to a study in Suffolk County, Long Island, more than half of the ticks collected were harboring at least one pathogen. The causative agent of Lyme disease, Borrelia burgdorferi was the most prevalent , followed by Babesia microti .

Furthermore, researchers found that among infected ticks collected, 45% were co-infected and carried up to 5 different pathogens. The most prevalent co-infections included Bartonella henselae and Rickettsia of the spotted fever group .

Herbal & Prescription Lyme Disease Antibiotics

In this article, you will learn how to build a Lyme disease herbal or prescription antibiotic treatment. Later, in this guide I provide nine sample herbal and prescription antibiotic treatment plans, including the dosing regimens I find effective.

The focus of this article is on Lyme germ treatment. For information about treating Lyme disease coinfections see

Before I describe these plans, you should be aware that chronic Lyme disease recovery requires more than antibiotics. I cannot emphasize this point strongly enough. Treating Borrelia, the Lyme germ, with antibiotics is complicated because limited research shows which treatment regimens work best. As a result, many Lyme-Literate Medical Doctors , like me, prescribe antibiotics based on theory, in addition to our collective observation, which is that combinations of antimicrobials work better than single agents alone. It is critical that a Lyme disease treatment regimen addresses the first ten steps outlined in my Lyme disease treatment guidelines, The Ross Lyme Support Protocol. These steps are designed to revive health and to boost the immune system. Even a year or more into treatment, when a person is feeling better, these steps are essential to speed recovery by supporting the immune system.

Antimicrobials That Kill Growing Phase Spirochetes

Extracellular

Penicillins

  • Amoxicillin 500 mg 1 to 2 pills 3 times a day. Alternatively as an alternative to IV antibiotics take 3 to 4 pills 3 times a day.
  • Amoxicillin/Clavulanic Acid 875 mg/125 mg 1 pill 2 times a day
  • Bicillin LA 2.4 million units IM 3 times a week with one day between each injection

Cephalosporins

  • Ceftriaxone 2 gm IV 2 times a day for 4 days in a row then off for 3 days of each 7 days
  • Cefotaxime 2 gm IV every 8 hours
  • Cefuroxime 500 mg 1 pill 2 times a day
  • Cefdinir 300 mg 1 pill 2 times a day

Additional IV Antibiotics

Vancomycin, imipenem, and ertapenem are possible alternatives if someone is allergic to Ceftriaxone or Cefotaxime.

Intracellular and Extracellular

  • Clarithromycin 500 mg 2 pills 2 times a day
  • Azithromycin 500 mg 1 time a day or 500 mg IV 1 time a day

Tetracyclines

  • Doxycycline 100 mg 1 or 2 pills 2 times a day or 200 to 400 mg mg IV 1 time a day
  • Minocycline 100 mg 1 pill 2 times a day

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Nymphal And Adult Ticks Shown To Be Co

Studies have looked at co-infection rates at different points in the ticks life cycle. In a comprehensive review of 61 different published reports, Nieto and Foley found that 2 to 5 percent of young nymphal I. scapularis ticks were reported to be co-infected with more than one microbe. Adult tick co-infection rates with B. burgdorferi varied widely between 1 to 28 percent across the reports analyzed :93-101, 2009). Although humans are more likely to be bitten by the smaller nymphal stage ticks , co-infection rates in adult ticks may provide important information about how tickborne diseases are transmitted.

Co-infection by some or all of these other microbes may make it more difficult to diagnose Lyme disease. Being infected by more than one microbe might also affect how the immune system responds to B. burgdorferi . NIAID-supported studies of mice found that co-infection with human granulocytic ehrlichiosiswhich is now known as anaplasmosisresults in more severe Lyme disease. Another study showed that when mice were co-infected with Babesia microti and B. burgdorferi, the presence of Babesia also enhanced the severity of Lyme disease, while the presence of B. burgdorferi appeared to limit the effects of Babesia.

Macrolide Plus Azole Plus Liposomal Essential Oils

Fight Lyme Disease and Co
  • clarithromycin 500 mg 1 pill 2 times a day
  • tinidazole 500 mg 1 pill 2 or 3 times a day.
  • liposomal cinnamon, clove & oregano oil 1 capsule 2 times a day

Key Points

  • Tinidazole treats cysts and can remove biofilms that block the immune system and antibiotics.
  • Liposomal cinnamon, clove & oregano oil can treat persister and growing forms of Lyme. Of the various herbal options to treat persiters – this is my go to persister herbal anti-microbial based on benefits I see in my practice.

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Can Lyme Disease Be Prevented

Not all cases of Lyme disease can be prevented. But you can help protect your family from tick bites. If you go into an area where ticks live, be sure to:

  • Stay in the middle of the trail, instead of going through high grass or the woods.
  • Wear closed shoes or boots, long-sleeved shirts, and long pants. Tuck pant legs into shoes or boots to prevent ticks from crawling up legs.
  • Use an insect repellent.
  • Consider treating clothing and gear with permethrin to repel ticks. When used properly, permethrin is safe for all ages. But don’t use it on clothing or other material a child may suck on or chew.
  • Wear light-colored clothing to help you see ticks more easily.
  • Shower and wash hair after being outside to remove ticks before they attach.

Is There A Vaccine For Lyme Disease

No vaccine against Lyme disease is currently available for people. Promising new vaccines are under development, among them some that target multiple tick-borne pathogens, and some that target tick saliva. . Vaccination against Lyme and other tick-borne diseases most likely will not remove the need for personal protective measures to prevent tick bites. Even the best vaccines are unable to provide perfect protection from infections, and new pathogens transmitted by ticks continue to be identified.

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Where Are Ticks Found

Ticks are found throughout the UK and in other parts of Europe and North America. There are a high number of ticks in the Scottish Highlands.

They can be found in any areas with deep or overgrown plants where they have access to animals to feed on.

They’re common in woodland and moorland areas, but can also be found in gardens or parks.

What Treatment Does Ilads Recommend For Lyme Disease

Babesia: A co-infection of Lyme Disease

Many patients with early Lyme have been treated with short courses of antibiotics and recovered. However, both in practice and in the scientific literature, it has been observed that a significant number of patients do not return to their pre-lyme health status.

The ILADS guidelines working group reviewed the available research and developed recommendations, based upon the best-available evidence, clinical expertise, and patient-centered values.

ILADS recommends a 4-6 week course of antibiotics as initial therapy for patients with early Lyme disease presenting with EM. Further treatment is guided by the clinical course and response to treatment. Although the guidelines do not discuss the treatment of non-EM early Lyme disease or disseminated disease, these topics are reviewed in the Fundamentals Course. For non-EM early disease, initial treatment is similar to that for EM. Patients with disseminated disease may need longer courses of antibiotics and antibiotic combinations.

ILADS emphasizes patient-centered, person specific care, and the importance of careful assessment and re-assessment of the full clinical picture to guide treatment decisions, initially and if symptoms persist or return.

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Lyme Disease Stage 3 Late Disseminated Infection

If the disease remains untreated, a persistent infection can occur after a few weeks or months, leading to prolonged bouts of arthritis and neurologic problems, such as concentration problems or personality changes. Fatigue is a prominent feature of both early and late stages.

If Lyme disease is left untreated in stage 3, patients may go on to develop severe and chronic symptoms that affect many parts of the body, including the brain, nerves, eyes, joints, and heart. Many disabling symptoms can occur, including permanent shooting pains, numbness, and tingling in the hands or feet may develop. Lyme disease is known as the great imitator because the symptoms which display if the disease is not treated, mimic many well-known conditions such as Rheumatoid Arthritis, Alzheimers and Fibromyalgia. For this reason it is very important to find a practitioner who can perform tests and make an accurate diagnosis.

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What Is A Co

Ticks can carry multiple infections at once. They do not only carry Lyme disease. This means they can also infect you with more than one disease when they bite and embed in your body.

Lyme is caused by the borrelia bacteria. This bacterium does not cause other infections. It is its own separate infection that causes its own negative symptoms which we refer to as Lyme disease. Along with Lyme, other unique infections from the tick enter your system, creating similar or additional negative symptoms, making it a co-infection.

There are multiple potential co-infections. All co-infections can make Lyme disease symptoms worse, more painful and more chronic. The most common are listed below, along with symptoms and treatments for each.

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Quinine Derivatives To Boost Intracellular Antibiotics

Intracellular

Inside of cells, Lyme may live in cave-like structures called vacuoles. In these vacuoles, Lyme germs create a hostile acidic environment that can limit the effectiveness of various antibiotics. Quinine derivatives, like hydroxychloroquine , can make the inside of cells more basic which can help the tetracyclines and macrolides mentioned above work better.

  • Hydroxychloroquine 200 mg 1 pill 2 times a day

Symptoms Of Lyme Disease

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Many people with early symptoms of Lyme disease develop a circular rash around the tick bite. The rash:

  • usually develops around 3 to 30 days after you’ve been bitten
  • is often described as looking like a bull’s-eye on a dart board
  • will be red and the edges may feel slightly raised
  • may get bigger over several days or weeks
  • is typically around 15 cm across, but it can be much larger or smaller

Some people may develop several rashes in different parts of their body.

Around 1 in 3 people with Lyme disease won’t develop a rash.

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Macrolide Plus Quinine Derivative Plus Azole Plus Methylene Blue

  • azithromycin 500 mg 1 pill 1 time a day
  • hydroxychloroquine 200 mg 1 pill 2 times a day
  • metronidazole 500 mg 1 pill 2 or 3 times a day
  • methylene blue 50 mg 2 times a day

Key Points:

  • Since azithromycin is not as effective as other macrolides like clarithromycin, hydroxychloroquine is used to increase the effectiveness.
  • Tinidazole could be substituted for the metronidazole because it may remove biofilms more effectively.
  • Methylene Blue can treat persister Lyme.

Recover From Lyme Disease At Lifeworks

If you havent been properly diagnosed or are still suffering from strange symptoms despite treatment, you owe it to yourself to get properly evaluated and treated.

We routinely treat patients from around the world, who come to our clinic, to recover from Lyme disease.

Most Lyme patients have already seen 6-8 other doctors without a resolution.

94% of these cases are fully resolved at LifeWorks Wellness Center.

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What Is Chronic Lyme Disease

There is a lot of disagreement about chronic Lyme disease. As ILADS defines it, chronic Lyme disease is a long-standing active bacterial infection with any member of the Borrelia burgdorferi family. For patients who have already been treated, this means that the bacteria was able to survive despite antibiotic therapy. ILADS doctors think that persistently ill patients, both treated and untreated, require carefully directed, targeted care, which may include extended courses of antibiotics and antibiotic combinations.

Herbal And Prescription Antimicrobials By Function

Babesia – An Important Co-infection of Lyme Disease

Be aware the doses I provide below are for adults. These same prescriptions can be used with children but have lower doses. For pediatric dosing, talk with your family physician or pediatrician. Tetracyclines can be used in children under eight, but there is a risk of tooth staining. This staining seems not to be an issue if they are used for a month or less.

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For Depression And Anxiety

Both psychotherapy and pharmacotherapy have proven benefits for improving mood. Psychotherapy has many different types such as supportive, dynamic, cognitive behavioral, dialectical behavior therapy, transference focused psychotherapy each of which offers benefit. Pharmacotherapy also has many different types. For depression the first-line options usually are SSRIs, SNRIs, Tricyclics or other agents with more unique modes of action.

A few noteworthy tips on anti-depressant agents:

  • Most anti-depressant agents also help in reducing anxiety. However the opposite isn’t necessarily true. Specific anti-anxiety agents such as clonazepam or diazepam may not necessarily help fight depression.
  • Most anti-depressants take three to eight weeks before an effect is seen. Therefore, it is unwise to stop an anti-depressant after only three or four weeks, as staying on it another two to three weeks may lead to a good response.
  • Dosage makes a difference. Some anti-depressants work fine at low doses some medications however are effective only at higher doses. Some medications are more effective as the dose is increased. Other antidepressants may have a therapeutic range one has to achieve at least a certain dosage .

How Can Lyme Disease Be Treated

At LifeWorks Wellness Center, we believe that the best treatment for Lyme disease is ozone therapy.

Ozone is a substance that is found at high atmospheric levels youve heard of the ozone layer. For medical purposes, ozone is created by sending oxygen through an electrical coil, causing it to have three atoms instead of two its no longer O2 its now O3. This third atom makes for oxygen that is supercharged, giving it superior medical properties.

Ozone works by increasing the amount of oxygen in your body. This helps it to heal by:

  • Detoxifying your liver
  • De-clogging your blood cells

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Understanding Lyme At The Cellular Level

To truly understand Lyme disease and why herbs are the best solution, you have to think at the cellular level. More than anything else, Lyme disease is an assault on cells of the body.

The human body is composed of trillions of living cells. Everything that happens in the body results from the actions of cells. Symptoms occur when cellular functions are compromised. The type of symptom reflects the types of cells being affected.

When the borrelia spirochetes spill into the bloodstream from the tick bite, their one goal is reaching tissues of the body. The immune systems job is keeping them from getting there.

As soon as the bacteria enter the bloodstream, white blood cells of the immune system immediately begin engulfing and destroying the bacteria with potent acid. Sometimes, however, the bacteria are able to turn off that process and stay alive inside the WBC. The compromised WBC unwittingly becomes a Trojan horse that transports the bacteria to tissues throughout the body even across the blood-brain barrier into the brain.

Despite their mechanisms of persistence, casualties on the bacteria side are high and most of the bacteria are eliminated. All it takes for success, however, is a few bacteria reaching tissues of the body joints, brain, heart, everywhere. Once on site at tissues, the remaining spirochetes immediately begin scavenging nutrients, such as collagen from joint tissue and myelin from nerve tissue to create more spirochetes.

Lyme Disease Stage 2 Early Disseminated Infection

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Untreated, the infection spreads through the bloodstream and lymph nodes within days to weeks, involving the joints, nervous system, and possibly the heart. Multiple rashes may erupt in other places. If the infection affects the nervous system in the second stage of Lyme disease, various acute neurological problems may appear. These include facial palsy, which is the loss of muscle tone on one or both sides of the face, as well as meningitis, which involves severe headaches, neck stiffness, and sensitivity to light. In addition, some case reports have described altered mental status, shooting pains that may interfere with sleep, as well as abnormal skin sensations.

Within days to weeks after the onset of local infection, the bacteria may begin to spread through the bloodstream and a rash may develop at sites across the body that bear no relation to the original tick bite.

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What Are Lyme Disease Co

When Lyme disease was first discovered in 1975, it was the only known tick-borne illness recognized by clinicians. The disease, which is caused by an infection with the bacterium Borrelia burgdorferi, is transmitted through the bite of a black-legged tick.

Today, ticks harbor multiple infectious pathogens that can be transmitted to humans through a tick bite or tainted blood transfusion. The Centers for Disease Control and Prevention now reports that a single tick can transmit multiple pathogens, including bacteria, viruses, and parasites. This can result in patients developing what is referred to as Lyme disease co-infections.

In fact, between 2004 and 2016, the CDC identified 7 new tick-borne microbes capable of infecting humans.

While most Lyme disease co-infections are acquired through the bite of an infected tick, several can be transmitted through contaminated blood transfusions. One investigation concluded, Aside from a Babesia infection, Anaplasma is the most frequent transfusion-transmitted with rapidly increasing clinical cases.

Why Isnt A Test Result Enough To Tell Me If I Have Lyme

Common tests for Lyme disease include ELISAs and Western blots. Both tests work by detecting the patients antibodies reacting to the Borrelia burgdorferi bacteria. Many factors affect that response and the tests ability to measure it, and can produce both false positive and false negative results. Although the CDC recommends a two-step testing process, consisting of an ELISA as a first test, followed by a Western Blot only if the ELISA is positive or uncertain, i.e. no further testing if the first step is negative, this testing scheme is insensitive. Additionally, positive results might reflect an old, rather than current infection. This is why testing is only one part of the information that contributes to making the diagnosis.

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