Sunday, August 14, 2022

What Is A Treatment For Lyme Disease

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How Can I Help Prevent Lyme Disease In A Child

Conventional or Natural Treatment for Lyme Disease? #86

There is no vaccine for Lyme disease. A child who has had the disease doesnt build up immunity and can get it again. But you can help prevent Lyme disease by protecting your child from tick bites.

Ticks cant bite through clothing, so dress your child and family in:

  • Long-sleeved shirts tucked into pants
  • Socks and closed-toe shoes
  • Long pants with legs tucked into socks

Choose light-colored clothing so that ticks can be easily seen. Check your child often for ticks, including:

  • Behind the knees, between fingers and toes, in underarms, and in the groin
  • In the belly button
  • In and behind the ears, on the neck, in the hairline, and on top of the head
  • Where underwear elastic touches the skin
  • Where bands from pants or skirts touch the skin
  • Anywhere else clothing presses on the skin
  • All other areas of the body and hair

Run fingers gently over the skin. Run a fine-toothed comb through your child’s hair to check for ticks.

Other helpful tips include:

  • When possible, use cleared or paved paths when walking through wooded areas and fields.
  • Shower after outdoor activities are done for the day. It may take up to 4 to 6 hours for ticks to attach firmly to skin. Showering may help remove any loose ticks.

Use insect repellents safely. The most common used against ticks are:

Check your pets for ticks. Talk with your pets veterinarian about tick repellent medicine.

Ongoing Symptoms Of Lyme Disease

A few people who are diagnosed and treated for Lyme disease continue to have symptoms, like tiredness, aches and loss of energy, that can last for years.

These symptoms are often compared to fibromyalgia and chronic fatigue syndrome.

It’s not clear why this happens to some people and not others. This means there’s also no agreed treatment.

Speak to a doctor if your symptoms come back, or do not improve, after treatment with antibiotics.

The doctor may be able to offer you further support if needed, such as:

  • referral for a care needs assessment
  • telling your employer, school or higher education institution that you require a gradual return to activities
  • communicating with children and families’ social care

Page last reviewed: 05 July 2021 Next review due: 05 July 2024

Chronic Lyme Disease Vs Post

Patients typically use the term chronic Lyme disease to describe the cluster of symptoms that started after getting Lyme disease and that persist despite having received a course of antibiotic treatment which has been deemed curative by the Infectious Diseases Society of America. Patients say, Im not cured. I have symptoms now that I never had before Lyme disease. Im fatigued 90% of the day. My muscles ache. My brain is in a fog. I cant think clearly any more. Im super sensitive to light and sound. What is going on? Chronic Lyme disease does exist Im a living example of it!

Whatever one calls it, the experience is the same. Most often these patients experience profound fatigue, pain, and/or cognitive impairment. Mild to moderate levels of depression and anxiety may also accompany these symptoms, as the functional limitations can lead to social isolation, inability to work, and loss of sense of ones identity as a provider, caretaker, or friend. Sometimes patients find themselves identifying with Job the just and good man in the Bible whose life was wrecked by illness, death of loved ones, and economic disaster he felt tormented by God.

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How You Get Lyme Disease

Lyme disease can be transmitted by the bite of a tick infected with Borrelia burgdorferi bacteria.

Ticks survive in many habitats but prefer moist areas with leaf litter or longer grass, like in woodland, grassland, moorland, heathland and some urban parks and gardens.

Ticks dont jump or fly but climb on to your clothes or skin if you brush past vegetation.

They then bite into the skin and start to feed on your blood. Being bitten doesnt mean youll definitely be infected as not all ticks carry the bacteria that cause Lyme disease.

If bitten by an infected tick, you are more likely to become infected the longer the tick remains attached and feeding.

Ticks are very small and their bites are not painful, so you may not realise you have one attached to your skin. It is important to check yourself for ticks after outdoor activities and remove any ticks promptly and safely.

Impact On Life Functioning

5 Warning Signs of Lyme Disease to Never Ignore

In order to capture the impact of health status on life functioning, the 36-item Short Form Health Survey, Version 2 , was administered at each study visit. It has been designed to study eight health attributes and has been shown to have high reliability and validity across a range of populations . Each of the 36 items in the measure loads onto one of eight subscales: Physical Functioning, Role Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role Emotional, and Mental Health. Raw scores of 0100 are generated for each subscale, and then scores are adjusted using a linear transformation to a mean of 50 and a standard deviation of 10 using 1998 general population norms . Lower scores reflect more negative impact of health status on life functioning. In our sample, we found Cronbachs of > 0.70 for all subscales, with 5/8 subscales > 0.90.

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Option 2 Supplement And Prescriptions:

In my experience, this prescription antibiotic-based option has a 10 percent better chance of working than the supplement-only option above. For best results use the two prescription medicines and the supplements at the same time. Note: This option is also a full Lyme infection support and treatment.

  • Clarithromycin 500 mg 1 pill 2 times a day. AND
  • Rifabutin 150 mg 2 times a day or 2 pills 1 time a day or Rifampin 300 mg 2 pills 1 time a day. AND
  • Liposomal Cinnamon, Clove, and Oregano Oil Combination 1 pill 2 times a day.

Symptoms Of Late Stage Lyme Disease

Your suffering has moved from an occasional inflammation flare-up to chronic pain in your muscles, tendons, and joints. You may have been diagnosed with some form of arthritis. Your headaches have become severe. You may even experience dizziness or vertigo.

Additional symptoms include a stiff neck, sleep disorders like insomnia, and numbness in your outer extremities. You may also lack the ability to focus, and paying attention when having conversations has become difficult. Your fatigue is so bad you sometimes do not want to attempt getting out of bed.

The worse symptom may be that you have tried to get the right help, but doctors have failed to give you an accurate diagnosis. Because of this, you may feel like you are crazy, or your friends and family may not believe you are in pain.

You may be wondering how you were able to reach late stage Lyme disease without proper treatment.

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Antimicrobials That Kill Growing Phase Cysts

Intracellular and Extracellular

Note: I work with the following agents as anti-cyst agents based on the mechanism by which these antibiotics work and some scientific experiments. For the Rifamycins, there are no laboratory experiments showing these agents work against cysts. Clinically, I see great benefit in using the Rifamycins as my anti-cyst agents – so I list them here.

Rifamycins

  • Rifampin 300 mg 2 pills 1 time a day or 1 pill 2 times a day
  • Rifabutin 150 mg 2 pills 1 time a day

Azoles

  • Tinidazole 500 mg 1 pill 2 or three times a day usually pulsed for four days on then three days off of each 7 days
  • Metronidazole 500 mg 1 pill 2 or three times a day usually pulsed for four days on then three days off of each 7 days.

Herbal

  • Grapefruit seed extract 250 mg 1 pill 2 times a day. Note this is an herbal antibiotic that I find as effective as the prescription options in this list.

Azlocillin Comes Out On Top

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The drug, which is not on the market, was tested in mouse models of Lyme disease at seven-day, 14-day and 21-day intervals and found to eliminate the infection. For the first time, azlocillin was also shown to be effective in killing drug-tolerant forms of B. burgdorferi in lab dishes, indicating that it may work as a therapy for lingering symptoms of Lyme disease.

Pothineni and Rajadas have patented the compound for the treatment of Lyme disease and are working with a company to develop an oral form of the drug. Researchers plan to conduct a clinical trial.

Rajadas is also a professor of bioengineering and therapeutic sciences at the University of California-San Francisco.

Other Stanford co-authors are Hari-Hara S. K. Potula, PhD, senior research scientist postdoctoral scholars Aditya Ambati, PhD, and Venkata Mallajosyula, PhD senior research scientist Mohammed Inayathullah, PhD and intern Mohamed Sohail Ahmed.

A researcher at Loyola College in India also contributed to the work.

The study was funded by the Bay Area Lyme Foundation and Laurel STEM Fund.

  • Tracie White

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How Was This Study Done

We evaluated and followed seventy-six participants with physician-documented erythema migrans, the classic bulls-eye rash associated with Lyme disease, and 26 healthy controls with no history of Lyme disease. Sixty-four inflammatory markers were measured in blood samples taken at each visit for a total of 6 visits over 1 year. Levels of inflammatory markers in patients with and without persistent post-treatment symptoms were compared to those in healthy controls.

Stage : Early Disseminated Lyme Disease

Early disseminated Lyme disease occurs several weeks to months after the tick bite.

Youll have a general feeling of being unwell, and a rash may appear in areas other than the tick bite.

This stage of the disease is primarily characterized by evidence of systemic infection, which means infection has spread throughout the body, including to other organs.

Symptoms can include:

  • disturbances in heart rhythm, which can be caused by Lyme carditis
  • neurologic conditions, such as numbness, tingling, facial and cranial nerve palsies, and meningitis

The symptoms of stages 1 and 2 can overlap.

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How Can I Prevent My Dog From Getting Lyme Disease

The key to prevention is keeping your dog from being exposed to ticks. Ticks are found in grassy, wooded, and sandy areas. They find their way onto an animal by climbing to the top of a leaf, blade of grass, or short trees, especially cedar trees. Here they wait until their sensors detect an approaching animal on which to crawl or drop. Keeping animals from thick underbrush reduces their exposure to ticks. Dogs should be kept on trails when walked near wooded or tall grass areas. Vaccination against Lyme disease is recommended for pets that live in endemic areas or that travel to areas where Lyme disease is prevalent.

“Vaccination against Lyme disease is recommended for pets that live in endemic areas or that travel to areas where Lyme disease is prevalent.”

What Causes Chronic Lyme Disease

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The CDC says 10% to 20% of people treated for Lyme disease develop ongoing symptoms. These can include fatigue, joint and muscle pain, and thinking problems. The symptoms can last more than 6 months.

No one knows what causes chronic Lyme disease. One theory is the infection damages tissues or alters the immune system.

Some pain experts think the immune systemâs reaction to the Lyme infection causes changes that increase pain sensations and contribute to fatigue and poor sleep.

More research is underway.

No matter the cause, the symptoms are real. But most patients get better over time.

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How To Avoid Tick Bites

To reduce the chance of being bitten:

  • cover your skin while walking outdoors and tuck your trousers into your socks
  • use insect repellent on your clothes and skin products containing DEET are best
  • stay on clear paths whenever possible
  • wear light-coloured clothing so ticks are easier to see and brush off

Early localized Lyme disease usually presents as an acute illness characterized by:

  • fever
  • headache
  • the presence of a single, localized skin lesion known as erythema migrans

Not all patients will present with an EM. Therefore, diagnosis should not be based solely on the presence of EM.

Most patients will present with EMs within 7 days of the initial tick bite. However, the incubation period can vary between 3 and 30 days.

The skin lesion is characteristically an annular erythematous lesion greater than 5 cm in diameter that:

  • slowly increases in size
  • is usually painless and non-pruritic

The lesion sometimes develops central clearing, but it can be more homogenously erythematous. In dark-skinned patients, the rash may appear more as a bruise.

Variations of an EM are highly suggestive of Lyme disease and can take the following forms:

  • blistering
  • blue-purple hues
  • a bulls-eye appearance

A skin lesion called erythema migrans can develop into a bulls-eye at the site of a tick bite. It is shown here on a patients upper arm.Footnote 1

Some Lyme disease skin lesions are uniformly red and do not appear with the classic ring.Footnote 1

  • fatigue

The Chance Of Getting Lyme Disease

Not all ticks in England carry the bacteria that causes Lyme disease.

But it’s still important to be aware of ticks and to safely remove them as soon as possible, just in case.

Ticks that may cause Lyme disease are found all over the UK, but high-risk places include grassy and wooded areas in southern and northern England and the Scottish Highlands.

Ticks are tiny spider-like creatures that live in woods, areas with long grass, and sometimes in urban parks and gardens. They’re found all over the UK.

Ticks do not jump or fly. They attach to the skin of animals or humans that brush past them.

Once a tick bites into the skin, it feeds on blood for a few days before dropping off.

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Differences And Similarities Between Chronic Fatigue Fibromyalgia And Ptlds

Many patients complaining about increased fatigue or generalised pain associate their condition with a preceding infection . Symptoms of PTLDS may have an aetiological and phenomenological overlap with chronic fatigue syndrome, fibromyalgia and other chronic pain syndromes.

As shown in table 7, the diagnostic criteria of chronic fatigue and fibromyalgia do substantially overlap with PTLDS, and the clinical differentiation between fibromyalgia, chronic fatigue and PTLDS may, by definition, be blurred. However, the diagnosis of PTLDS requires a previously documented infection with B. burgdorferi and a plausible association between Lyme borreliosis and the beginning of persisting symptoms that were not present before the onset of B. burgdorferi infection.

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History And Physical Examination

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The clinical diagnosis of Lyme disease can be straightforward in patients with a history of tick exposure and the characteristic finding of an erythema migrans rash.12 The CDC has defined erythema migrans rash as an expanding red macule or papule that must reach at least 5 cm in size .11 According to the Infectious Diseases Society of America guidelines, erythema migrans rash is the only clinical manifestation sufficient to make the diagnosis of Lyme disease in the absence of laboratory confirmation.20 Although one study concluded that primary care physicians in a Lyme diseaseendemic area of France correctly identified erythema migrans in 72 percent of patients,22 the study was limited by lack of complete clinical information for the participants.

A number of conditions resemble erythema migrans however, the rapid and prolonged expansion of an erythematous lesion is unique to erythema migrans.11 Lesions most often occur at anatomic sites that are unusual for cellulitis and other conditions that mimic erythema migrans therefore, a complete skin examination should be performed before excluding erythema migrans.20

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Symptoms Of Lyme Disease

People with Lyme disease may react to it differently, and the symptoms can vary in severity.

Although Lyme disease is commonly divided into three stages early localized, early disseminated, and late disseminated symptoms can overlap. Some people will also present in a later stage of disease without having symptoms of earlier disease.

These are some of the more common symptoms of Lyme disease:

  • a flat, circular rash that looks like a red oval or bulls-eye anywhere on your body
  • other flu-like symptoms

These symptoms may occur soon after the infection, or months or years later.

Your child may have Lyme disease and not have the bulls-eye rash. According to an early study, results showed roughly 89 percent of children had a rash.

Lyme disease is best treated in the early stages. Treatment for early localized disease is a simple 10- to 14-day course of oral antibiotics to eliminate the infection.

Medications used to treat Lyme disease include:

  • doxycycline, amoxicillin, or cefuroxime, which are first-line treatments in adults and children
  • cefuroxime and amoxicillin, which are used to treat women who are nursing or breastfeeding

Intravenous antibiotics are used for some forms of Lyme disease, including those with cardiac or central nervous system involvement.

After improvement and to finish the course of treatment, healthcare providers will typically switch to an oral regimen. The complete course of treatment usually takes 1428 days.

Who’s At Risk And Where Are Ticks Found

The risk of getting Lyme disease is higher:

  • for people who spend time in woodland or moorland areas
  • from March to October because more people take part in outdoor activities

Ticks are found throughout the UK and in other parts of Europe and North America. There are a high number of ticks in the Scottish Highlands.

It’s thought only a small proportion of ticks carry the bacteria that cause Lyme disease. Being bitten doesn’t mean you’ll definitely be infected. However, it’s important to be aware of the risk and speak to a GP if you start to feel unwell.

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