Access To Lyme Disease Testing Services
This guidance on the laboratory diagnosis of Lyme disease is intended for healthcare professionals in the UK. Patients concerned about possible Lyme infection should consult an appropriate healthcare professional, for example their GP, in the first instance.
Health professionals wishing to discuss a possible case or ascertain local arrangements for testing should contact a local Infection specialist .
NHS testing for Lyme disease is available through local service providers and the Rare and Imported Pathogens Laboratory at PHE Porton where ISO15189 accredited confirmatory testing is also provided. RIPL is also introducing a testing service for neurological Lyme disease.
RIPL provides medical and laboratory specialist services to the NHS and other healthcare providers, covering advice and diagnosis of a wide range of unusual bacterial and viral infections, including Lyme disease.
RIPL continuously updates its methods and will make further information on Lyme disease diagnostic testing available as it arises.
How Much Does A Lyme Disease Test Cost
The cost of a Lyme disease test depends on what type of test is performed an ELISA test or a combination of ELISA and western blot tests.
Averagely, the cost for an ELISA test for Lyme disease is in the vicinity of $120 or more. If you include a confirmation western blot test, it can attract an additional $130 or more. More details on pricing can be referenced on our website.
Although an ELISA test might come back negative, it is best to combine it with a western blot test because not everyone shows the rash or bulls eye symptoms of Lyme disease.
After a successful diagnosis and treatment, it is equally important to do a follow-up test for Lyme disease years later to be sure that any similar flu-like symptoms are something else and not the same disease reoccurring.
Are Lyme Disease Tests Accurate
Most at-home Lyme disease test kits screen for certain IgG and IgM antibodies that are part of the immune response against an infected tick bite. It takes time for these antibodies to appear in the bloodstream, and therefore a Lyme disease test will typically be most accurate once these antibodies have developed.
If you take a test too early, you may receive a false negative, as antibodies are not yet present in the blood, despite you having the infection. It takes between four and six weeks for antibodies to be detectable.
Whether you test positive for Lyme disease antibodies or not, you should still follow up with your healthcare provider. The results of an at-home Lyme disease test should not be taken as an official diagnosis for the condition.
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An Introduction To Lab Testing
Lyme disease tests can serve as valuable resources for the diagnosis and treatment of tick-borne disease. But its important not to get too hung up on the results.
The problem of chronic Lyme disease, cant be solved exclusively by looking at lab results, which is something I know from personal experience. In fact, becoming overly obsessed with lab results can hinder the recovery process.
Lab work provides a snapshot of whats going on inside your body. But multiple other factors including your symptoms, the length of time youve had them, and clinical presentation, as well as the environments in which you live, work, and travel all factor into making an accurate diagnosis.
Furthermore, the human body is an immensely complex biological machine, with millions of different biochemical functions happening simultaneously. Lab tests provide an ever-so-small glimpse at certain key functions of different systems in the body. From those indicators, determinations can be made about how well the body is functioning and whether illness is present.
Laboratory assessment, however, is far from absolute. Because the human body is so complex, the ability of lab testing to predict a specific chronic illness, such as one from a tick-borne disease, is often limited. All labs are subject to variability and different interpretations.
The Chance Of Getting Lyme Disease
Not all ticks in England carry the bacteria that causes Lyme disease.
But it’s still important to be aware of ticks and to safely remove them as soon as possible, just in case.
Ticks that may cause Lyme disease are found all over the UK, but high-risk places include grassy and wooded areas in southern and northern England and the Scottish Highlands.
Ticks are tiny spider-like creatures that live in woods, areas with long grass, and sometimes in urban parks and gardens. They’re found all over the UK.
Ticks do not jump or fly. They attach to the skin of animals or humans that brush past them.
Once a tick bites into the skin, it feeds on blood for a few days before dropping off.
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What Is Lyme Disease How Does My Dog Get Infected
Lyme disease is an infectious disease caused by bacteria called Borrelia. The bacteria are most commonly carried by the deer tick . Infection occurs when a dog is bitten by an infected tick. It appears that the disease is not transmitted until the tick has fed for approximately 12 hours. The tick itself becomes infected by feeding on infected mice, birds, deer, and other animals.
Investigation Of Suspected Lyme Disease
Erythema migrans is a clinical diagnosis and does not require confirmation by laboratory testing. Lyme disease is not a notifiable disease so there is no statutory requirement to notify clinically suspected cases to the local Health Protection Team.
The 2018 NICE Lyme disease guideline provides detailed advice about when a diagnosis of Lyme disease should be suspected and about which tests to use and when.
The NICE Lyme disease guideline also contains a useful summary diagram of the routine serological testing recommendations for Lyme disease.
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Stage : Late Disseminated Lyme Disease
Stage 3 or late disseminated Lyme disease is the final stage of the disease. A person may enter this stage if they did not receive treatment for Lyme disease in the early stages, or if their symptoms persisted despite treatment. As such, doctors sometimes refer to this stage as chronic or post-treatment Lyme disease .
Stage 3 Lyme disease can occur after an infected tick bites a person.
A person with stage 3 Lyme disease may experience additional symptoms, including:
- severe joint pain and swelling, known as chronic Lyme arthritis
- heart palpitations or irregular heartbeat, due to Lyme carditis
- inflammation of the brain and spinal cord
- mental fogginess
How Do They Test For Lyme Disease
Lyme disease is best tested using two different blood testing methods. These are:
- The Enzyme-linked Immunosorbent Assay test: In a nutshell, this test will look for signs that your body is trying to fight off Lyme disease by producing antibodies. However, the ELISA test may come back negative even when a person is infected by the Borrelia burgdorferi bacteria. False-negatives can occur during the early stages of the disease, where the infected persons body has not produced enough antibodies to fight off the B. burgdorferi bacteria. For this reason, reliable diagnosis is not usually based only on the ELISA test results.
- Western Blot test: Heres a simple way to explain the western blot test without getting into all the nitty-gritty details of what it does and how it does it. Put simply, it separates the blood proteins and detects antibodies to the bacteria causing the Lyme disease. Usually, when an ELISA test comes back positive, a western blot test is performed to confirm the diagnosis.
Ideally, the CDC recommends standard two-tier testing to confirm the veracity of the Lyme disease test accuracy. Together, the ELISA and western blot tests are 99.9% accurate.
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The Blood Tests Can Have False Positives
The blood tests can trigger false positives, suggesting that you have the disease when you really dont. This can happen in up to one out of four tests.
This can lead to unnecessary treatment with antibiotics. These drugs are usually safe, but they sometimes cause side effects, such as nausea, vomiting, diarrhea, and increased sensitivity of the skin to sunlight. In rare cases, they can even cause dangerous allergic reactions.
Using too many antibiotics can also lead to the growth of drug-resistant bacteria. This means that bacteria in your body may get stronger and more difficult to treat with antibiotics in the future.
A false positive can also lead to more unneeded blood tests, urine tests, X-rays, and doctor visits.
If you have a false positive, you may not get treated for the real cause of your pain. For example, rheumatoid arthritis is a disease that causes joint pain. It can lead to permanent and severe joint damage if you do not start taking the right medicines as early as possible.
Elisa And Western Blot
The first part of the ELISA test acts as a preliminary investigation to see if further testing is needed. A negative result typically warrants no further testing, but a positive one does. The first test is highly sensitive and the second highly specific. This makes sure that only people with Lyme disease are diagnosed and treated.
The Western blot test is a type of blood test that aims to single out certain proteins known as antigens. It is used to identify an active infection of Lyme disease. Although sometimes accurate, however, this test is inherently flawed because methods and criteria for interpreting results can change from lab to lab.
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Can Lyme Disease Be Detected By A Blood Test
In a word: yes!
A blood test does not only detect Lyme disease it is the most accurate and preferred test for diagnosing the disease. If a patient with Lyme disease shows signs that the central nervous system has been affected by the disease, western blot testing on the cerebrospinal fluid can be performed. If ordering from Walk-In Lab, a doctors note is not needed. Just pick your Lyme disease test and place your order online.
When To Speak With A Doctor
Early diagnosis and treatment are crucial to help prevent late Lyme disease and its symptoms, including chronic Lyme arthritis and Lyme carditis.
A person should consult with a doctor if they have a tick bite or believe a tick has bitten them after visiting tick-prone regions.
They should also seek medical help if they experience any signs and symptoms of Lyme disease. These
The following are commonly asked questions about Lyme disease tests.
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Serological Testing Of Csf For The Diagnosis Of Neurological Lyme Disease
Serological testing for neurological Lyme disease is based on demonstrating intrathecal synthesis of Borrelia-specific antibodies in CSF. For laboratory testing for neurological Lyme disease, separate IgG and IgM ViraChip® serology assays are performed on CSF and paired serum and the results compared.
CSF samples must be tested in parallel with a contemporaneous serum sample and protein and immunoglobulin levels compared between the two sample types to produce a meaningful result.
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Th Medical Group News And Updates
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Most Accurate: Dna Connexions
Test looks for Borrelia burgdorferi, in addition to 10 other common vector-borne pathogens
Does not accept insurance
No assistance after testing results are received
DNA ConneXions is a company known in the scientific community for its detailed analysis of lab results. This at-home Lyme disease test, for example, is superior to the others because it tests for all 10 vector-borne pathogens, while others only test the most common two or three.
DNA ConneXions earned our most accurate distinction because of its detailed Lyme disease test, as well as its impressive laboratory with a biosafety level 2 lab with a CLIA license. This means the company knows its stuff and is able to help people with accurate testing.
After DNA ConneXions receives your urine sample, it will review your sample, and email you your results within two to three weeks. It is unclear how much support the company offers after you receive your results, so it would be wise to schedule an appointment with your primary care doctor. This is to ensure that your body heals entirely if your Lyme disease test is positive.
This is the most expensive kit on this list, costing about $650 for the full Lyme panel. As of now, it will not work with insurance companies or accept HSA. The DNA ConneXions lab, however, is one of the most trusted laboratories worldwide.
What Is An At
An at-home Lyme disease test will typically be a blood finger prick test.
If you have been exposed to the bacteria Borrelia that leads to the infection of Lyme disease, your body will have created two antibodies to fight it off. The test will look for the presence of both types of antibodies, known as immunoglobulin M and immunoglobulin G .
You will receive your test kit along with account information so that you can get your test results as soon as they are ready. Follow the manufacturers instructions exactly as they are described.
Each test has different instructions, so its very important that you read the kits detailed information before getting started.
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Where Is Lyme Disease Found
In the United States, Lyme disease has been reported in every state, but over 95% of cases are from the Northeastern, Mid-Atlantic, and upper Midwestern states, with a small number of cases reported along the West Coast, especially Northern California. In Canada, Lyme-positive dogs are found mostly in southern Ontario and southern Manitoba, with a small number of cases in southern Quebec and the Maritime provinces.
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Symptoms Of Lyme Disease
Lyme disease progresses in stages. Early-onset also called early localized, symptoms include a rash that may or may not look like a bullseye, fatigue, flu-like symptoms, sore throat, headaches, stiff neck, and sore muscles and joints.
You do not have to have all these symptoms to have Lyme disease. Just one can signal a problem. As you can see, it would be easy for a general practitioner to misdiagnose your symptoms for something more common.
Inattention to, or misdiagnosis of, early localized symptoms can lead to the next stage, early dissemination. Your symptoms will worsen in this stage because the bacteria is spreading throughout your body rather than staying in one spot. You may also have periods of numbness or weakness in the arms and legs, vision problems, and bells palsy.
If your symptoms are not appropriately addressed by now, you run the risk of your Lyme disease entering the late dissemination stage. This is often referred to as chronic Lyme disease. At this stage, your Lyme disease is likely interfering with your ability to function and enjoy life.
Your symptoms include all of the above, only worse. You may also experience sleep disturbances, memory problems, inability to concentrate or focus, and you may find it hard to carry on lengthy conversations. This happens because your brain is struggling to process information.
This stage can become more dangerous for your health and can include heart rhythm disturbances.
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Reason : The Type Of Test Used
PCR Test: Antibody Test :
|Borrelia Culture Test:This test looks for the actual presence of the Lyme bacteria in a persons blood. It completely skips the middle man, antibodies, of antibody testing, and is considered the closest test to 100% accuracy in detecting an active Lyme infection in a person. The problem with this test is that it relies on a living Lyme bacterium to be cultured , and the nature of the Lyme bacteria is that it does not survive long outside of its host, even in cyst-form. This is why Advanced Laboratory Services, the lab that performs the Borrelia Culture Test, needs your blood sample within 24 hours of being withdrawn.|
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Late Lyme Disease Symptoms
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Treatments For Lyme Disease
Antibiotics are used as the first line of treatment. However, Lyme-literate doctors administer them through an infusion directly into your bloodstream to attack the bacteria directly. Other advanced treatments include hyperthermia, apheresis, biofilm eradication, antioxidant therapy, and protocols to fight oxidative stress.
Because you can contract Lyme disease more than once, your treatment must include learning more about Lyme prevention methods. If you spend time outdoors, cover as many body parts as you can and spray yourself with repellant. Avoid areas with high, brushy grass. When you come in from outside, do tick checks on yourself and your pets. Take a shower and wash your clothes.
To learn more about testing, treatments, or prevention, contact us today. Our Lyme-literate physicians are eager to work with you.