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Lyme Disease Antibodies Total And Igm With Reflex To Western Blot On Positive Test Cost Is Between $15500 And $29650

Lyme Disease – The Basics, Testing, Symptoms, & Treatment Options

None Lyme Disease Antibodies, Total and IgM, With Reflex to Western Blot on Positive test cost minimal is in RequestATest with price $155.00. Lyme Disease Antibodies, Total and IgM, With Reflex to Western Blot on Positive test cost max is in Private MD with price $184.99. This laboratory test is available in 2 online lab test stores.

  • $155.00

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  • $208.00

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    Order from Walk-In Lab

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  • $267.00


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    Understanding Of Lab Tests Results

    Please visit the site associated with The American Association for Clinical Chemistry for better understanding of tests. There you will find the most detailed and full information regarding lab tests. In “common questions” tab you will find answers on the most common questions.

    In addition, you can use a special form to ask the question. It is useful, if there is no answer on your question on the web site. A laboratory scientist will answer your question. It is a part of voluntary service provided by the American Society for Clinical Laboratory Science.

    What Is The Most Accurate Test For Lyme Disease

    Lyme disease is more common than many people think. Figures from the Center for Disease Control suggest that roughly 300,000 Lyme disease cases occur every year in the US.

    The numbers are alarming, but it gets worse as finding accurate diagnostic tests can be challenging. Although the disease is treatable, it is nearly impossible to tackle it effectively if it is not diagnosed accurately and early enough.

    Late detection can lead to severe health problems such as arthritis, heart blockage, and inability to concentrate, among other problems.

    Given the prevalence and seeming elusiveness of the disease, some of the logical questions concerned persons would ask are: what is the most accurate test for Lyme disease? And when should I get checked for Lyme disease? This article will proffer answers to these and many other related questions. But first, a little background would be in order.

    Recommended Reading: Lyme Bell’s Palsy Treatment

    Pcr For B Burgdorferi

    Short for Polymerase Chain Reaction, a PCR tests directly for borrelia DNA in the hosts blood, tissues, or urine. Historically, PCR has had limited accuracy, but improvements in technique are allowing PCR for microbial DNA to be the future of testing. At some point, it may be possible to define a persons entire microbiome.

    For now, testing is available for the most common species of borrelia and many common species of coinfections with other stealth microbes. Testing is most accurate during acute infection, and much less accurate during chronic infection.

    Again, the bottom line is that if you have many or most symptoms of chronic Lyme disease, then you are likely harboring at least one species of borrelia and several other species of stealth microbes no matter what the testing shows.

    Many companies are offering microbial DNA testing, but a few are taking the lead. DNA Connexions tests DNA in either blood or urine specimens for three species of borrelia and several of the most common coinfections. Testing kits are available online.

    Lyme Disease Pcr Blood Test

    Infectious Disease Lab Benefits

    The Lyme PCR test is used to aid in the diagnosis of Lyme Disease. This test detects the genetic material of the bacteria which causes Lyme Disease. Results for this test are quantitative and provide a numerical result for the level of bacteria detected. PCR testing is highly sensitive and may be able to detect the presence of Lyme Disease sooner than an antibody test. As a screening, this test still has the possibility of a false positive so results should be confirmed with a Lyme Disease Immunoblot test. A PCR test can be useful for patients who are receiving antibiotic treatment for Lyme Disease but are still experiencing symptoms. In this case, A PCR test may be able to detect an active infection with more accuracy than an antibody test.

    This test is designed to detect Borrelia Burgdorferi Sensu Stricto, the bacterial strain associated with Lyme Disease in the United States. It is not appropriate for people who suspect they have contracted Lyme Disease outside of the US.

    This test is typically ordered when someone is monitoring their treatment for Lyme Disease or has been treated but is still experiencing symptoms. While a PCR test can be used as a screening, an antibody test such as the Lyme Disease Total and IgM Antibody is more commonly ordered for this purpose.

    Turnaround time for the Lyme Disease PCR test is typically 7-10 business days.

    Detection Period:


    Recommended Reading: What Percentage Of Ticks Carry Lyme Disease

    Medical Testings Dirty Little Secret And How You Can Protect Yourself

    Diagnosis is a journey. Over the next few months, this column will take you through the various steps of that journey to help you get an accurate diagnosis. Last month we focused on what to do if your symptoms are dismissed or ignored. Each month well show you where the pitfalls may be, how to be proactive, and how to partner with the healthcare team to reduce your risk.

    Patrick Sheridan with his son Cal

    Patrick Sheridan was relieved to hear he didnt have cancer. The initial report on the tumor removed from his spine said it was benign. However, no one at the neurosurgeons office was aware that corrected test reports were neither seen by the surgeon nor communicated to Pat. Six months later, when his pain returned, Pat and his doctor learned that the unseen test results noted he had an aggressive, malignant sarcoma requiring urgent treatment. It was too late and Pat died when he was 45.

    Sarah Boyle was just 25 when she had months of chemotherapy followed by a double mastectomy for her invasive breast cancer. Thats when she learned she never actually had breast cancer. The labs official statement blamed human error for misdiagnosing a cancer-free patient with invasive cancer. Despite enduring difficult and unnecessary treatment and surgery, today Sarah is focused on helping prevent this kind of error for others.

  • Inaccurate Test Results
  • Closing the Loop on Test Results

    What you can do:

    Understanding Test Results

    What you can do:

    Inaccurate Test Results

    An Introduction To Lab Testing

    Lyme disease tests can serve as valuable resources for the diagnosis and treatment of tick-borne disease. But its important not to get too hung up on the results.

    The problem of chronic Lyme disease, cant be solved exclusively by looking at lab results, which is something I know from personal experience. In fact, becoming overly obsessed with lab results can hinder the recovery process.

    Lab work provides a snapshot of whats going on inside your body. But multiple other factors including your symptoms, the length of time youve had them, and clinical presentation, as well as the environments in which you live, work, and travel all factor into making an accurate diagnosis.

    Furthermore, the human body is an immensely complex biological machine, with millions of different biochemical functions happening simultaneously. Lab tests provide an ever-so-small glimpse at certain key functions of different systems in the body. From those indicators, determinations can be made about how well the body is functioning and whether illness is present.

    Laboratory assessment, however, is far from absolute. Because the human body is so complex, the ability of lab testing to predict a specific chronic illness, such as one from a tick-borne disease, is often limited. All labs are subject to variability and different interpretations.

    Recommended Reading: How To Treat Lyme Disease Flare Ups

    What Do Testing Kits Typically Include

    Depending on the method of collection, testing kits may include:

    • a device to collect the blood, urine, or saliva sample
    • instructions
    • a container to ship the sample back to the lab
    • a shipping label

    Some kits come with a bandage, wipes, and a biohazard bag. Kits may contain extras such as Styrofoam holders, labels, or tubes with varying solutions inside.

    What Is Lyme Disease

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    Lyme disease is an illness caused by infection with a bacteria that is spread through the bite of certain kinds of ticks. Symptoms can affect the skin where the bite occurred or elsewhere on the skin and may progress to affect other parts of the body. A family of bacteria, known as Borrelia, causes Lyme disease.

    Also Check: Common Signs Of Lyme Disease

    Persistent Lyme Disease Symptoms Arent Helped By Long

    Microbiologist Elli Theel, who directs the Infectious Diseases Serology Laboratory at Mayo Clinic, calls the 2015 study incredibly promising. The sensitivity they showed just in early Lyme disease patients was very high, the highest Ive actually seen, she said.

    In an upcoming publication, the researchers also showed that metabolomics can differentiate Lyme from a similar tick-borne disease called southern tick-associated rash illness . The disease causes similar symptoms as Lyme, including a bullseye rash, and occurs in overlapping geographic regions. Currently there is no laboratory test to diagnose STARI, and little is known about how the disease progresses and how to treat it, something Molins hopes will change with better testing.

    Are Test Results Accurate

    When looking at your test results, itâs important to know that laboratory methods can have a significant impact on the outcome of Lyme disease antibody testing.

    Analyzing blood samples for Borrelia antibodies is a technical process. In some cases, cross-reactivity can cause a positive result when you havenât actually had a Borrelia infection. Cross-reactivity is when antibodies to other infectious organisms are detected by the test as if they were antibodies to Borrelia.

    The CDC has created standards for testing in order to reduce the chances of this kind of false positive result. Studies have found that results are most reliable in labs that use these CDC standards.

    The timing of blood antibody testing can also affect accuracy because IgM and IgG antibodies develop at different rates. Taking the test too early after Borrelia exposure can lead to a false negative result even if you have an active infection.

    Beyond antibody blood testing, many test methods marketed for Lyme disease are not proven to be accurate. The CDC recommends against the use of unvalidated tests, including the following:

    • Urine tests such as urine antigen or PCR tests
    • Blood testing with PCR or any laboratory method other than an enzyme immunoassay, immunofluorescence assay, or the Western Blot, also called immunoblot, method
    • Cell culture, immunofluorescence staining, or cell sorting of Borrelia bacteria
    • Lymphocyte transformation tests
    • CD57 lymphocyte assays

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    When To Speak With A Doctor

    Early diagnosis and treatment are crucial to help prevent late Lyme disease and its symptoms, including chronic Lyme arthritis and Lyme carditis.

    A person should consult with a doctor if they have a tick bite or believe a tick has bitten them after visiting tick-prone regions.

    They should also seek medical help if they experience any signs and symptoms of Lyme disease. These

    The following are commonly asked questions about Lyme disease tests.

    Best For Dna Test: Selfdecode

    Infectious Disease Lab Benefits

    Self Decode

    • Tests for chronic conditions related to Lyme disease like PTLDS

    • Results in 6-8 weeks

    SelfDecode searches for more than Lyme disease. When you take an at-home test through this company, you’ll receive an entire mock-up of your DNA. You will know if you ever had Lyme disease in the past, as well as if you are susceptible to PTLDS, a chronic condition triggered by Lyme Disease.

    The test involves taking a simple cheek swab, after which the test is mailed back to the company’s lab. After six to eight weeks, you will receive your results via email, and you will be contacted by a medical professional to see what the next steps are.

    This is a subscription service that costs just under roughly $100 a year, so you will be able to check yourself for Lyme disease regularly when the test is shipped out. This service is great for those who enjoy the outdoors and are exposed to ticks a lot.

    SelfDecode’s test is not covered by insurance, but most primary care physicians will accept these results.

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    Is There A Lyme Disease Test Kit

    Blood collection kits are available for at-home Lyme disease testing. Lyme disease test kits can cost as less as $20 and as much as $100 or more. Using a Lyme disease test kit is as simple as pricking your finger and smearing or collecting the blood onto the kit for testing.

    However, testing for Lyme disease in a more controlled environment such as a lab or clinic is preferable as qualified healthcare professionals are likely to perform a more reliable test.

  • Center for Disease Control and Prevention . Data and surveillance. Retrieved from
  • Eugene D. S. . Lyme disease. N Engl J Med 2014 370:1724-1731. Retrieved from
  • Zeller J. L. . Lyme disease. JAMA. 2007 297:2664. Retrieved from
  • Center for Disease Control and Prevention . Diagnosis and testing. Retrieved from
  • Waddell L. A., et al. . The accuracy of diagnostic tests for Lyme disease in humans, a systematic review and meta-analysis of North American research. PLoS One. 2016 11: e0168613. Retrieved from

    Lyme Testing: Accurate When Used Appropriately

    A 2016 systematic review that included 8 studies of CDC-recommended two tier test performance in Late Lyme showed Lyme antibody testing to be 99.4% sensitive and 99.3% specific** in North America.

    In other words, out of 100 people with Late Lyme disease, 99-100 of them will test positive. Out of 100 people who may believe they have Late Lyme disease but do not, 99-100 of them will test negative.

    Misinformation can convince patients to ignore or misinterpret negative tests to justify a false Chronic Lyme diagnosis.

    Recommended Reading: Ways To Test For Lyme Disease

    Two Enzyme Immunoassays Performed Sequentially In A 2

    Individual tests using different targets often are not susceptible to the same false-positive or false-negative effects. If a positive result from 2 tests is required to diagnose a particular disease, one expects greater specificity than would be obtained by either test alone. This principle is applied frequently in infectious disease diagnostics. For example, the sequential use of 2 different rapid tests for human immunodeficiency virus infection has been recommended to improve the positive predictive value of point-of-contact testing . In Lyme disease, the opportunity to apply this principle has arisen with the availability of next-generation EIAs. Next-generation EIAs are dissimilar from WCS EIAs and, in some cases, to each other. For example, the VlsE outer-surface protein and its C6 immunodominant epitope are not well represented in WCS EIAs. Thus VlsE or C6 EIAs are different from WCS EIAs.

    What The Experts Say

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    According to the CDC:

    • Patients who have had Lyme disease for longer than 4-6 weeks, especially those with later stages of illness involving the brain or the joints, will almost always test positive.
    • A patient who has been ill for months or years and has a negative test almost certainly does not have Lyme disease as the cause of their symptoms.
    • Serologic testing is generally not useful or recommended for patients with single EM rashes. For this manifestation, a clinical diagnosis is recommended.

    Experts around the world agree with the CDC. A 2018 French review of 16 Lyme diagnostic guidelines from 7 countries revealed a global consensus regarding diagnosis at each stage of the infection. The only outlier was the pseudoscience group German Borreliosis Society , a German counterpart to the pseudoscience group ILADS.

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    Final Comment About Lyme Tests

    I opened this article stating that Lyme is always a clinical diagnosis. Again a test does not diagnose a disease. Also be aware based on the concepts of predictive value and prevalence I present above. Based on these concepts there is a great chance of a false positive test in someone who does not have Lyme disease symptoms. For more information see How to Diagnose Chronic Lyme Disease.

    Finally, I am often asked about test from a lab called DNA Connexions. This lab runs a urine pcr test for Lyme and coinfections. I do not order tests from this lab because they have not done any validation studies to prove their tests are accurate. Be aware they have done an effective job marketing to the naturopathic doctor community and some integrative medicine physicians. The reason I am very skeptical is the number of times I saw people in my Seattle practice with positive DNA Connexions testing for bartonella or babesia who simply did not have any symptoms of these coinfections. I suggest staying away from testing from this lab.

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