Sunday, August 14, 2022

Medicine Used For Lyme Disease

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Patients Turning To Herbal Remedies

Doxycycline and Lyme Disease Treatment

Because patients are currently turning to herbal remedies to fill the treatment gaps left by antibiotics, this research is a critical step in helping clinicians, as well as patients, understand which ones may offer the most potential benefit.

According to this study, carried out by Prof. Ying Zhangs group at the Johns Hopkins Bloomberg School of Public Health, the seven herbal medicines that have the ability to kill B. burgdorferi in test tubes are:

  • Cryptolepis sanguinolenta
  • Uncaria tomentosa
  • Cistus incanus
  • Scutellaria baicalensis

It is important to note that each of these products have the potential to produce significant side effects in patients, and should be taken only under advisement of a clinician knowledgeable of their capabilities and toxicities.

Of these products, the Cryptolepis sanguinolenta extract caused complete eradication, while doxycycline and cefuroxime and other active herbs did not. This extract has been used for the treatment of malaria as well as the tick-borne infection Babesia, a malaria-like parasite.

This study is believed to be the first time this extract has been documented to have a potential impact on B. burgdorferi, and additional laboratory and clincial studies should be conducted to investigate the potential role Cryptolepis sanguinolenta could play in the treatment of Lyme disease.

Antimicrobials That Kill Growing Phase Spirochetes

Extracellular

Penicillins

  • Amoxicillin 500 mg 1 to 2 pills 3 times a day. Alternatively as an alternative to IV antibiotics take 3 to 4 pills 3 times a day.
  • Amoxicillin/Clavulanic Acid 875 mg/125 mg 1 pill 2 times a day
  • Bicillin LA 2.4 million units IM 3 times a week with one day between each injection

Cephalosporins

  • Ceftriaxone 2 gm IV 2 times a day for 4 days in a row then off for 3 days of each 7 days
  • Cefotaxime 2 gm IV every 8 hours
  • Cefuroxime 500 mg 1 pill 2 times a day
  • Cefdinir 300 mg 1 pill 2 times a day

Additional IV Antibiotics

Vancomycin, imipenem, and ertapenem are possible alternatives if someone is allergic to Ceftriaxone or Cefotaxime.

Intracellular and Extracellular

  • Clarithromycin 500 mg 2 pills 2 times a day
  • Azithromycin 500 mg 1 time a day or 500 mg IV 1 time a day

Tetracyclines

  • Doxycycline 100 mg 1 or 2 pills 2 times a day or 200 to 400 mg mg IV 1 time a day
  • Minocycline 100 mg 1 pill 2 times a day

How Can I Prevent My Dog From Getting Lyme Disease

The key to prevention is keeping your dog from being exposed to ticks. Ticks are found in grassy, wooded, and sandy areas. They find their way onto an animal by climbing to the top of a leaf, blade of grass, or short trees, especially cedar trees. Here they wait until their sensors detect an approaching animal on which to crawl or drop. Keeping animals from thick underbrush reduces their exposure to ticks. Dogs should be kept on trails when walked near wooded or tall grass areas. Vaccination against Lyme disease is recommended for pets that live in endemic areas or that travel to areas where Lyme disease is prevalent.

“Vaccination against Lyme disease is recommended for pets that live in endemic areas or that travel to areas where Lyme disease is prevalent.”

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Is Amoxicillinas Effective As Doxycycline For Lyme Disease

You might be askingyourself, Can amoxicillin treat Lyme disease? The answer is yes. Anamoxicillin treatment for early Lyme disease is widely prescribed, but foramoxicillin to have the same efficacy as doxycycline, patients will have totake almost 10 times the amount 500 mg three times a day, for two to threeweeks. Deciding which antibiotic to go with depends on the patients ability tokeep up with the antibiotics course and how far along the disease hasprogressed.

Amoxicillin is alsoprescribed in patients who are pregnant because its still effective againstthe bacteria but doesnt pose the same risks as doxycycline on the pregnancyand unborn child. Doxycycline is also avoided in children under eight yearsold, whereas amoxicillin can be taken by children who have been infected withLyme.

What To Expect With Medication Treatment For Lyme Disease

My treatment plan. There are many ways to treat Lymeâ¦

You might have some side effects from both the disease and the medication treatment. Your doctor might suggest other things to make you feel more comfortable. Antidepressants and pain relief treatment may help. You might also be asked to do physical therapy, stretching or exercises or change your diet.Some people still have symptoms of Lyme disease after being treated. This is call post-Lyme disease syndrome. Doctors don’t know why some people get it and others don’t. It usually makes you feel tired and have sore muscles. Using more antibiotics doesn’t help, but other treatments may help you feel better.

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What Is Neurologic Lyme Disease

Neurologic symptoms of Lyme disease occur when the Lyme disease bacteria affect the peripheral or central nervous systems.

  • Cranial nerve involvement: When the cranial nerves are affected, facial palsy can occur on one or both sides of the face.
  • Peripheral nerve involvement: When the peripheral nerves are affected, patients can develop radiculoneuropathy which can cause numbness, tingling, shooting pain, or weakness in the arms or legs.
  • Central nervous system involvement: When the central nervous system is affected, Lyme meningitis can cause fever, headache, sensitivity to light, and stiff neck.

Out of every 100 patients whose cases are reported to CDC, 9 have facial palsy, 4 have radiculopathy, and 3 have meningitis or encephalitis. Because of reporting practices, this statistic may overestimate how often these manifestations are seen by clinicians.

Different Types Of Medication For Lyme Disease

Doctors prescribe different medications for children and adults and for women who are pregnant or breastfeeding. You’ll take antibiotics for 10 to 21 days, depending on your doctor’s advice.Medication treatment is more intense if the bacteria show signs of progressing into your central nervous system. This is what happens with time when Lyme disease is left untreated. Instead of taking pills, you’ll be given an antibiotic through a needle. This is called intravenous treatment. The medicine will work faster by going straight into your bloodstream. People are given IV treatment for two to three weeks.

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Considerations While On Lyme Treatment

Antibiotics can wipe out beneficial intestinal flora, leading to a wide variety of additional health problems. It is important to take probiotics while on antibiotics to maintain a healthy balance of gut bacteria. Furthermore, antibiotics may interact with other drugs, supplements or food. The National Institutes of Healths MedLinePlus website gives information about drug interactions.

Lyme Disease Antibiotics Overview

5 Tips to Prevent Tick Bites and Getting Lyme Disease | Johns Hopkins Medicine

The following are four general rules I use to develop a Lyme disease antibiotic regimen.

  • Rule 1. Combine antibiotics to treat all forms of the germ.
  • Rule 2. Combine antibiotics to treat Lyme living outside and inside of cells.
  • Rule 3. Combine antibiotics that work in different ways to attack the germ from different angles.
  • Rule 4. Treat all growth phases of Lyme at the same time – this means treatments should include antimicrobials that address persisters in addition to the growth phase of the term.

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Antibiotics Alone Are Unlikely To Get You Well

This is the second time I am making this point because it is very important. It is essential to your recovery that, at a minimum, your treatment address the steps outlined in my Lyme disease treatment guidelines: The Ross Lyme Support Protocol. Even a year or more into your treatment, these ten steps are essential to resuscitate and support the immune system.

Natural Remedies For Lyme Disease

Lyme disease is a bacterial infection caused by the bacterium Borrelia burgdorferi. It is spread through the bite of infected ticks.

Ticks are very small, and their biteswhich can occur anywhere on the bodyare usually painless, so you may not immediately be aware that you have been bitten. In most cases, the tick must be attached to the body for 24 hours before Lyme disease is transmitted.

The signs and symptoms of Lyme disease usually start within three to 30 days after youve been bitten by an infected tick. Many people experience flu-like symptoms after being bitten, while more serious symptoms show up weeks after the bite. Early signs and symptoms of Lyme disease include:

  • Chills
  • Rash
  • Swollen lymph nodes

If left untreated, symptoms can worsen to include Bells palsy , severe headaches, muscle, joint, and tendon pain, cardiac problems, and neurological disorders.

Most cases of Lyme disease can be managed and treated with two to three weeks of antibiotics. Depending on the severity of your symptoms and how long after the bite you were diagnosed, you may need a longer course of antibiotics to clear up the infection. Many people turn to natural remedies to help treat Lyme disease.

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What To Expect At Home

Home care for dogs with Lyme disease is relatively straightforward. Doxycycline is usually given by mouth twice daily for at least 30 days. Improvement in the dogs symptoms should be noted within 24-48 hours. If the dogs condition fails to improve in 72 hours or worsens at any time, call your veterinarian.

Two Standards Of Care For Lyme Disease Treatment

Lyme Disease and Bartonella: More Common Than You Think

There is significant controversy in science, medicine, and public policy regarding Lyme disease. Two medical societies hold widely divergent views on the best approach to diagnosing and treating Lyme disease. The conflict makes it difficult for patients to be properly diagnosed and receive treatment.

One medical society, the Infectious Diseases Society of America , regards Lyme disease as hard to catch and easy to cure with a short course of antibiotics. IDSA claims that spirochetal infection cannot persist in the body after a short course of antibiotics. The group also denies the existence of chronic Lyme disease.

In contrast, the International Lyme and Associated Diseases Society , regards Lyme disease as often difficult to diagnose and treat, resulting in persistent infection in many patients. ILADS recommends individualized treatment based on the severity of symptoms, the presence of tick-borne coinfections and patient response to treatment.

LDo believes that patients and their doctors should make Lyme disease treatment decisions together. This requires that patients be given sufficient information about the risks and benefits of different treatment options. Then, patient and health care provider can collaborate to reach an informed decision, based on the patients circumstances, beliefs and preferences.

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What Is The Treatment For Lyme Disease

The first-line standard of care treatment for adults with Lyme disease is doxycycline, a tetracycline antibiotic. Other antibiotics that have activity against borrelia include the penicillin-like antibiotic, amoxicillin, and the second generation cephalosporin, Ceftin. The mainstay of treatment is with oral antibiotics, but intravenous antibiotics are sometimes indicated for more difficult to treat cases of neurologic-Lyme disease, such as meningitis, and cases of late Lyme arthritis.

Chelation Therapy For Lyme Disease

Some people believe Lyme disease symptoms are linked to heavy metal toxicity from materials like lead or mercury. Chelation therapy is a method of removing heavy metals from the bloodstream.

Its done using a type of medication called a chelator or chelating agent. This medication binds to metals in the bloodstream, collecting them into a compound that can be processed by your kidneys and released in urine.

Chelation therapy is an effective treatment for a buildup of heavy metals. But theres no evidence that heavy metals contribute to Lyme disease, and chelation therapy wont treat the underlying infection.

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Treatment For Erythema Migrans

People treated with appropriate antibiotics in the early stages of Lyme disease usually recover rapidly and completely. Early diagnosis and proper antibiotic treatment of Lyme disease can help prevent late Lyme disease.

Treatment regimens listed in the following table are for the erythema migrans rash, the most common manifestation of early Lyme disease. These regimens may need to be adjusted depending on a persons age, medical history, underlying health conditions, pregnancy status, or allergies. Consult an infectious disease specialist regarding individual patient treatment decisions.

Treatment regimens for localized Lyme disease.

Age Category
100 mg, twice per day orallyN/A
500 mg, three times per day orallyN/A
500 mg, twice per day orallyN/A
4.4 mg/kg per day orally, divided into 2 doses100 mg per dose
50 mg/kg per day orally, divided into 3 doses500 mg per dose
30 mg/kg per day orally, divided into 2 doses500 mg per dose

*When different durations of antibiotics are shown to be effective for the treatment of Lyme disease, the shorter duration is preferred to minimize unnecessary antibiotics that might result in adverse effects, including infectious diarrhea and antimicrobial resistance.

NOTE: For people intolerant of amoxicillin, doxycycline, and cefuroxime, the macrolide azithromycin may be used, although it is less effective. People treated with azithromycin should be closely monitored to ensure that symptoms resolve.

Risk Factors For Post

Chinese Medicine & Lyme Disease Pt.2: Lyme Disease Defined in Chinese Medicine

Youre at a greater risk for post-treatment Lyme disease syndrome if youre infected by the bite of a diseased tick. If the infection progresses to the chronic stage, your symptoms might continue for weeks, months, or even years after the initial tick bite.

You may also be at a higher risk for these long-term symptoms if youre not treated with the recommended antibiotics. However, even people who receive antibiotic therapy are at risk. Because the cause of post-treatment Lyme disease syndrome is unknown, theres no way to determine whether it will progress to the chronic stage.

Typically, the symptoms of post-treatment Lyme disease syndrome resemble those that occur in earlier stages. People with persistent symptoms often experience lingering episodes of:

  • fatigue

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Symptoms Of Post Treatment Lyme Disease

  • Include severe fatigue, musculoskeletal pain, & cognitive problems
  • Can significantly impact patients health and quality of life
  • Can be debilitating and prolonged

Our research indicates the chronic symptom burden related to PTLD is significant. Although often invisible to others, the negative impact on quality of life and daily functioning is substantial for PTLD sufferers.

The chronic symptom burden related to Lyme disease is considerable, as shown on the left side of the graph above, and statistically significantly greater than the aches and pains of daily living experienced by the control group, on the right.

What Are The Second Stage Signs And Symptoms Of Lyme Disease

The symptoms of second stage, early disseminated, Lyme disease can be difficult to attribute. Symptoms include severe fatigue, fever, pain, intermittent weakness and achiness of the muscles and joints, numbness in arms and legs, vision changes, and cognitive dysfunction such as short-term memory difficulties and problems multitasking. These symptoms are not specific for Lyme disease and can make the diagnosis of second stage Lyme disease very challenging.

More recognizable Lyme disease nervous system manifestations include facial paralysis , or meningitis with severe headache and stiff neck. Notable cardiac manifestations include passing out or feeling faint from an abnormally slow heart rate, irregular heart palpitations, or unexplained difficulty tolerating exercise. Meningitis and carditis are both potentially serious Lyme disease conditions and warrant immediate medical attention.

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Macrolide Plus Azole Plus Liposomal Essential Oils

  • clarithromycin 500 mg 1 pill 2 times a day
  • tinidazole 500 mg 1 pill 2 or 3 times a day.
  • liposomal cinnamon, clove & oregano oil 1 capsule 2 times a day

Key Points

  • Tinidazole treats cysts and can remove biofilms that block the immune system and antibiotics.
  • Liposomal cinnamon, clove & oregano oil can treat persister and growing forms of Lyme. Of the various herbal options to treat persiters – this is my go to persister herbal anti-microbial based on benefits I see in my practice.

Lyme Disease Treatment: 2 Herbal Compounds May Beat Antibiotics

Lyme Disease Medication, Supplements &  More

Lyme disease transmitted via tick bite affects thousands of people in the United States and around the world. Currently, doctors use antibiotics to treat it, but could plant-based remedies be more effective?

Lyme disease is an infectious disease caused by the bacterium Borrelia burgdorferi .

The disease spreads to humans through the bite of a tick that carries the bacterium, and it affects an estimated each year in the U.S. alone.

Currently, healthcare professionals choose between three antibiotics in the treatment of Lyme disease. These are doxycycline, cefuroxime, and amoxicillin.

Sometimes, however, antibiotics are not effective in eradicating all traces of B. burgdorferi from the system, which means that the disease can persist.

When this happens, bacterial cells that have developed antibiotic resistance can continue to proliferate. These are known as persister cells .

Because of this, researchers have been looking into alternative modes of fighting the bacterium, and their first line of inquiry has focused on natural remedies.

In 2018, an in vitro study suggested that 10 plant-derived essential oils could help fight off B. burgdorferi.

Now, researchers from the Johns Hopkins Bloomberg School of Public Health in Baltimore, MD, and from the California Center for Functional Medicine and Focus Health in Berkeley, have conducted a new study that has led them to believe that two specific plants may lead to more effective therapies against Lyme disease.

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Chronic Lyme Disease Or Postlyme Disease Syndrome

Following an episode of Lyme disease that is treated appropriately, some persons have a variety of subjective complaints . Some of these patients have been classified as having chronic Lyme disease or postLyme disease syndrome, which are poorly defined entities. These patients appear to be a heterogeneous group. Although European patients rarely have been reported to have residual infection with B. burgdorferi , this has yet to be substantiated either in a large series of appropriately treated European patients or in a study of North American patients. Residual subjective symptoms that last weeks or months also may persist after other medical diseases . It has also been recognized that the prevalence of fatigue and/or arthralgias in the general population is > 10% .

In areas of endemicity, coinfection with B. microti or the Ehrlichia species that causes HGE may explain persistent symptoms for a small number of these patients . Randomized controlled studies of treatment of patients who remain unwell after standard courses of antibiotic therapy for Lyme disease are in progress. To date, there are no convincing published data showing that repeated or prolonged courses of oral or iv antimicrobial therapy are effective for such patients. The consensus of the IDSA expert-panel members is that there is insufficient evidence to regard chronic Lyme disease as a separate diagnostic entity.

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