Cofactors That Increase The Risk Of Lyme Disease
You now know that your dog is more likely to develop symptoms of Lyme disease if there is a coinfection. So of course, you want to know what these underlying cofactors are.
This is where it gets weird. Dr Rau discovered that certain vaccines were cofactors for Lyme disease. And that includes the tick-borne meningoencephalitis vaccine.
Now, it isnt known whether the Lyme vaccine for dogs is a cofactor. And thats because they conducted the research on the human population. But, we can tell you that the LYMERix human Lyme disease vaccine was only used for 18 months between 1998 and 2000. After that they pulled it off the market amidst reports of serious adverse events and because the vaccine may have caused Lyme-like arthritis.
And they have not developed a new Lyme vaccine for humans since. Did you catch that?
They pulled the human Lyme vaccine from the market because of safety concerns. Yet vaccination for Lyme disease is still recommended for your dogs.
Evidence is mounting that it could be this very vaccine that acts as a cofactor allowing Lyme to progress from flu-like symptoms into a debilitating disease.
Dr Rau explains the relationship in this short video:
Other important cofactors for Lyme disease include:
- Chronic inflammation
Neurological Infections In Travelers/immigrants
Many infectious diseases that affect the nervous system can be acquired from other parts of the United States or other parts of the world. In the United States, several regional viruses and fungi can cause encephalitis and/or meningitis that individuals coming from endemic regions may have been exposed to. Worldwide, neurocysticercosis, poliomyelitis, malaria, schistosomiasis, rabies, chikungunya virus, dengue fever, leptospirosis, Tick-Borne encephalitis virus, cycloviruses, and melioidosis are some of the infections that can be acquired which affect the nervous system.
Achy Stiff Or Swollen Joints
Joint pain and stiffness, often intermittent, are early Lyme symptoms. Your joints may be inflamed, warm to the touch, painful, and swollen. You may have stiffness and limited range of motion in some joints .
Pain may move around. Sometimes your knees may hurt, whereas other times its your neck or your heels. You may also have bursitis . Bursae are the thin cushions between bone and surrounding tissue.
The pain may be severe, and it may be transitory. More than one joint may be affected. Most often the large joints are involved .
People often attribute joint problems to age, genetics, or sports. Lyme should be added to that list, as these statistics indicate:
- One study estimates that 80 percent of people with untreated Lyme have muscle and joint symptoms .
- Fifty percent of people with untreated Lyme have intermittent episodes of arthritis .
- Two-thirds of people have their first episode of joint pain within six months of the infection .
- Use of anti-inflammatory drugs may mask the actual number of people with joint swelling .
Joint pain that comes and goes, or moves from joint to joint, could be a sign of Lyme.
Unexplained Pain And Other Sensations
Some people with Lyme may have sharp rib and chest pains that send them to the emergency room, suspecting a heart problem 00090-7/abstract%20″ rel=”nofollow”> 27).
When no problem is found, after the usual testing, the ER diagnosis is noted as an unidentified musculoskeletal cause.
You can also have strange sensations like skin tingling or crawling, or numbness or itchiness 00090-7/abstract%20″ rel=”nofollow”> 27).
Other symptoms have to do with cranial nerves.
- Ear-ringing . Tinnitus can be a nuisance, especially at bedtime when it seems to get louder as youre trying to fall asleep. About 10 percent of people with Lyme experience this (
- Hearing loss. One study reported that 15 percent of Lyme patients experienced loss of hearing .
- Jaw pain or toothaches that are not related to actual tooth decay or infection.
Using Cbd Oil In Your Dogs Treatment Plan
There is anecdotal evidence that suggests CBD is a holistic solution that can improve your dogs overall mood and increase their appetite. The increase in appetite is important because Lyme disease in dogs can reduce their appetite. Although CBD oil is not a treatment for Lyme disease in dogs, it can help stimulate appetite and can help mitigate any pain or discomfort your dog may be feeling. If your dog has been diagnosed with Lyme disease you should speak with your trusted veterinarian to come up with a treatment plan that suits your dog.
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Neurologic Complications Of Hiv
HIV affects the nervous system in a variety of ways and can do so either directly by the virus itself or indirectly through opportunistic infections or dysregulated inflammatory reactions. Direct effects the virus has on the nervous system include cognitive disorders causing memory loss, sensory neuropathy causing pain in the hands and/or feet) spinal cord disease causing difficulty walking, meningitis causing headaches, muscle wasting causing weakness and/or muscle pain. Sometimes HIV can be the cause of strokes or seizures, as well.
What Is Neurologic Lyme Disease
Neurologic symptoms of Lyme disease occur when the Lyme disease bacteria affect the peripheral or central nervous systems.
- Cranial nerve involvement: When the cranial nerves are affected, facial palsy can occur on one or both sides of the face.
- Peripheral nerve involvement: When the peripheral nerves are affected, patients can develop radiculoneuropathy which can cause numbness, tingling, shooting pain, or weakness in the arms or legs.
- Central nervous system involvement: When the central nervous system is affected, Lyme meningitis can cause fever, headache, sensitivity to light, and stiff neck.
Out of every 100 patients whose cases are reported to CDC, 9 have facial palsy, 4 have radiculopathy, and 3 have meningitis or encephalitis. Because of reporting practices, this statistic may overestimate how often these manifestations are seen by clinicians.
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Can My Animal Get Infected Despite Being Vaccinated
Yes. Some animals have been infected despite vaccination. The most common reasons are low or short-lasting vaccine antibodies in the individual animal. It is advisable to monitor the vaccine response annually to ensure the animal develops sufficient antibodies in response to vaccination. Vaccine antibodies can be quantified with the Lyme Multiplex assay as early as two weeks following vaccination or anytime afterwards.
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Does Lyme Disease Affect The Brain And Nervous System
Lyme disease affects the nervous system. This statement is both accurate and terrifying since, for many of us, damage to the brain is the most feared consequence of disease. However, when it comes to Lyme disease, much of this fear is misplaced. Lyme disease can affect the lining of the brain, a disorder known as meningitis. Other than causing fever and bad headaches, this form of meningitis is remarkably benign nobody has ever died of it, and it has rarely if ever caused significant damage to any patients brain. On extremely rare occasions, the infection can involve the brain or spinal cord, disorders that are now extraordinarily rare. Other patients can develop inflammation of various nerves, e.g., the nerves that control the muscles on one side of the face this might occur in about 5% of untreated individuals. Other nerves can be affected, but even less frequently.
When considering these disorders, it is essential to recognize some key facts. First, the infection is highly responsive to antibiotics. Second, if the facial nerve has been severely damaged, there may be some residual weakness after treatment. However it is extraordinarily rare for there to be any permanent damage to the brain itself.
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My Dog Was Diagnosed With Anaplasmosis What Is It
Anaplasmosis is a tick-borne disease caused by the infectious bacterial organism Anaplasma phagocytophilum. It is transmitted through bites of the deer tick and western black-legged tick. A lesser form of anaplasmosis is caused by Anaplasma platys and is transmitted by the brown dog tick. Anaplasmosis has been reported worldwide in a wide variety of animals.
How Do You Check Your Dog For Ticks
To check your dog for ticks, gently work your fingers through their fur and down to the skin. Feel for ticks or other bumps around their entire body. If you notice something off, part your dogs fur, and do a visual check.
Ticks love attaching onto the following areas:
Soft areas behind the dogs ears
Under the collar
If you find a tick, use a tick comb to sift through the fur for unwanted bugs hitching a ride on your furry friend. If you find a tick on your pet, remove it using fine-tipped tweezers. There are also products available specifically for removing ticks. Grab the tick as close to your dogs skin as possible. Slowly pull straight up to remove the tick from your dog.
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How Is The Lyme Multiplex Assay Different From The Assay My Veterinarian Can Perform
Your veterinarian can perform a quick assay in-house that checks for antibodies against only one B. burgdorferi surface protein. The in-house assay cannot detect early infection, cannot determine vaccination status, and does not quantify the amount of antibodies your animal is producing. Quantifying antibodies is an important measure for successful treatment and to confirm cure from Lyme disease.
For Animals That Have Not Been Vaccinated Can Osp A Values Be Positive How Should This Be Interpreted
Antibodies to OspA have previously been interpreted as markers for vaccination. Non-vaccinated animals usually have low values for antibodies to OspA, while vaccinated animals develop these antibodies. OspA antibodies have been shown to protect from infection with B. burgdorferi.
However, there is accumulating evidence that antibodies to OspA can occur without vaccination. First, residual OspA is present on the bacterial surface at the time of transmission to an animal. This causes a low and transient OspA antibody response early after infection. Second, antibodies to OspA have also been associated with treatment-resistant Lyme arthritis and with development of autoimmunity in human patients. Similarly, OspA antibodies in non-vaccinated dogs or horses can be considered as markers of chronicity and disease severity.
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What Is Late Lyme Disease
Lyme disease, also known as Lyme borreliosis, is caused by an infection with the bacteria Borrelia burgdorferi. This bacteria is disseminated through tick bites. Infected ticks usually bite small mammals, who do not develop any kind of infection from the bacteria. When humans are exposed to B. Burgdorferi from a tick bite, however, they can develop Lyme disease.
People who work outside or spend time in woodland areas, where there is greater potential for exposure to tick bites, are most at risk of infection.
Lyme disease is a condition which progresses in stages:
Key Points For Healthcare Providers
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Can Lyme Disease Be Prevented
To prevent Lyme disease, you should lower your risk of getting a tick bite:
- Avoid areas where ticks live, such as grassy, brushy, or wooded areas. If you are hiking, walk in the center of the trail to avoid brush and grass.
- Use an insect repellent with DEET
- Treat your clothing and gear with a repellant containing 0.5% permethrin
- Wear light-colored protective clothing, so you can easily see any ticks that get on you
- Wear a long-sleeve shirt and long pants. Also tuck your shirt into your pants and your pant legs into your socks.
- Check yourself, your children, and your pets daily for ticks. Carefully remove any ticks you find.
- Take a shower and wash and dry your clothes at high temperatures after being outdoors
Centers for Disease Control and Prevention
Treatment For Lyme Disease In Dogs
Veterinarians treat dogs with Lyme disease through a combination of medical therapy and supportive care. A 4-to 6-week course of antibiotics will be prescribed for dogs with clinical signs of Lyme disease, as well as for dogs that have a high antibody level, even if they are asymptomatic. Many owners see improvement within a few days. However, a second round of antibiotics is often required, as the infection may persist through the first round of treatment.
Severe cases of Lyme disease will acquire additional therapy to treat affected kidneys, heart, or nerves, along with supportive care like intravenous fluids. Re-checking blood work is recommended six months after completing antibiotic therapy to determine if treatment has been successful.
There is some debate within the veterinary community as to whether dogs should be treated if they test positive for Lyme disease but are asymptomatic and have a low antibody level. Your veterinarian will speak to you about different options so that you can come up with the best treatment plan for your dog.
Lyme disease can stay in your dogs body even with antibiotics. In these cases, the disease often flares up when a dogs immune system is suppressed or weakened, such as during periods of stress. The same antibiotic can be used to treat repeated recurrences of Lyme disease. Unlike other types of infections, the lingering infection is not a direct result of antibiotic resistance.
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Lyme Disease: Symptoms & Side Effects
Lyme disease is a tick-born illness with over 150 symptoms, usually involving multiple systems. There are three stages of Lyme disease: early localized, early disseminated, and late persistent. If left untreated, it may progress into long-term disabilities. However, it is important to note that Lyme disease can lie dormant in your body for a prolonged period of time, and will invade when your immune system is compromised.
- Irritable bladder
- Pain in eyes, or swelling around eyes
- Oversensitivity to light
- Pain in ears, oversensitivity to sound
- Ringing in one or both ears
- Unexplained weight gain or loss
- Extreme fatigue
- Symptoms seem to change, come and go
- Pain migrates to different body parts
- Early on, experienced a flu-like illness, after which you have not since felt well
- Twitching of facial or other muscles
- Facial paralysis
- Tingling of nose, cheek, or face
- Stiff or painful neck, creaks and cracks
- Jaw pain or stiffness
- Difficulty with concentration or reading
- Going to the wrong place
- Speech difficulty
- Any joint pain or swelling
- Stiffness of joints, back, neck
- Muscle pain or cramps
- Burning or stabbing sensations in the body
- Weakness or partial paralysis
- Numbness in body, tingling, pinpricks
- Poor balance, dizziness, difficulty walking
- Increased motion sickness
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What Are The Symptoms Of Lyme Disease In Dogs
Lyme disease is often more challenging to identify in dogs than in humans, primarily due to the lack of a rash. While humans typically develop a characteristic “bullseye” rash around the location of the tick bite causing the infection, dogs don’t develop this rash. Instead, behavioral cues are used to identify canine Lyme disease.
Those symptoms include:
- Loss of appetite and/or weight loss
- Lameness in one or more parts of the body
- Stiffness or pain in one or more parts of the body
- Overall loss of energy
While tick bites are the cause of Lyme disease, the development of symptoms takes place much later than the initial bite. Your dog may not show symptoms of Lyme disease until two to five months after being infected. The signs of Lyme disease in dogs can also bear similarities to the symptoms of other health conditions. For this reason, it’s crucial that dog owners seek out a veterinary diagnosis if they suspect their pet has canine Lyme disease.
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Canine Lyme Disease: How It Spreads
A question that many dog owners might have is about the probability of a Lyme disease diagnosis in their canine companions. Lets look into how the disease spreads and the probability of a Lyme disease diagnosis from a tick bite before answering the question- can Lyme disease in dogs cause seizures?
Its important to know that the tick species that have been identified as carriers of the bacteria Borrelia burgdorferi can harbor this bacterium at any stage of development. Suppose your dog is bitten by a tick carrying this bacterium. In that case, there is a possibility that your dog might be infected with Lyme disease.
It takes approximately two days for the tick to transmit the Lyme disease-causing bacteria after biting a dog. Therefore, the risk of transmission of this bacterium is the highest during periods or seasons when the adults and nymphs are actively on the lookout for hosts.
Infection rates of ticks vary quite significantly, but they can be as high as 50%. This means that just because a dog has been bitten by a tick carrying the bacteria doesnt necessarily mean that he/she will be infected with Lyme disease. Not every dog that has been exposed to the bacteria will have Lyme disease.
As already mentioned, the complete transmission of the bacteria from the tick to the dog takes about 2 days. So, its a good idea to regularly check your furry friend for ticks and remove them immediately .
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