Why This Is Important
The use and duration of antibiotics for chronic Lyme disease treatment is controversial because there is no biomarker that can determine whether the Lyme bacteria has been eradicated in CLD patients. Patients are often told that either chronic Lyme disease does not exist or that it is incurable. If this were true, we would not expect more well and substantially improved patients to be taking antibiotics. Instead, we might have expected the percentage of people using antibiotics to be roughly the same among the patient subgroups.
Antimicrobials That Kill Growing Phase Spirochetes
Extracellular
Penicillins
- Amoxicillin 500 mg 1 to 2 pills 3 times a day. Alternatively as an alternative to IV antibiotics take 3 to 4 pills 3 times a day.
- Amoxicillin/Clavulanic Acid 875 mg/125 mg 1 pill 2 times a day
- Bicillin LA 2.4 million units IM 3 times a week with one day between each injection
Cephalosporins
- Ceftriaxone 2 gm IV 2 times a day for 4 days in a row then off for 3 days of each 7 days
- Cefotaxime 2 gm IV every 8 hours
- Cefuroxime 500 mg 1 pill 2 times a day
- Cefdinir 300 mg 1 pill 2 times a day
Additional IV Antibiotics
Vancomycin, imipenem, and ertapenem are possible alternatives if someone is allergic to Ceftriaxone or Cefotaxime.
Intracellular and Extracellular
- Clarithromycin 500 mg 2 pills 2 times a day
- Azithromycin 500 mg 1 time a day or 500 mg IV 1 time a day
Tetracyclines
- Doxycycline 100 mg 1 or 2 pills 2 times a day or 200 to 400 mg mg IV 1 time a day
- Minocycline 100 mg 1 pill 2 times a day
How You Get Lyme Disease
If a tick bites an animal carrying the bacteria that cause Lyme disease, the tick can become infected. The tick can then transfer the bacteria to a human by biting them.
Ticks can be found in any areas with deep or overgrown plants where they have access to animals to feed on.
They’re common in woodland and moorland areas, but can also be found in gardens or parks.
Ticks don’t jump or fly. They climb on to your clothes or skin if you brush against something they’re on. They then bite into the skin and start to feed on your blood.
Generally, you’re more likely to become infected if the tick is attached to your skin for more than 24 hours. Ticks are very small and their bites are not painful, so you may not realise you have one attached to your skin.
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Seven Herbal Medicines Can Kill Lyme Disease Bacteria In Test Tube
Researchers have determined that seven herbal medicines are highly active in test tubes against B. burgdorferi, the bacteria that causes Lyme disease, compared to the control antibiotics, doxycycline and cefuroxime.
Published in the journal Frontiers in Medicine, the laboratory study was funded by the Bay Area Lyme Foundation and supported in part by The Steven & Alexandra Cohen Foundation.
Researchers at Johns Hopkins Bloomberg School of Public Health and colleagues at the California Center for Functional Medicine and FOCUS Health Group, Naturopathic collaborated on the study.
Since traditional antibiotic approaches fail to resolve symptoms in up to 25% of patients treated for Lyme disease and many suffer disabling effects of the disease, there is a need for novel treatment proven effective against B. burgdorferi, said the papers co-author Sunjya K. Schweig, MD, CEO and co-director, California Center for Functional Medicine and Scientific Advisory Board Member, Bay Area Lyme Foundation.
Summary 21 Lyme Disease Natural Treatment Options
Lyme is a complex disease that involves a long list of symptoms that can become debilitating if its not treated right away.
In addition to antibiotics traditionally used to treat Lyme, practicing holistic, natural strategies can help the body heal and grow stronger over time. I hope this post gave you many strategies to help you fight Lyme disease naturally.
Do you know someone with Lyme or other tick-borne diseases? What strategies do you use to fight Lyme Disease naturally?
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Penicillin Plus Azole Plus Lipsomal Cinnamon Clove & Oregano Oil
- amoxicillin 500 mg 4 pills 3 times a day
- tinidazole 500 mg 1 pill 2 or 3 times a day for 4 days on and 3 days off in 7-day cycles.
- liposomal cinnamon, clove, and oregano oil capsules 1 pill 2 times a day.
Key Points:
- This is a very high dose of amoxicillin, which is four times stronger than physicians prescribe for other infections like ear infections. I consider this dose to be nearly as effective as IV antibiotics.
- This is a pulse dose regimen of the tinidazole. It may be more effective than continuous regimens.
- The essential oils are added to treat persister Lyme.
Hunting For Alternative Drug
Frustrated by the lack of treatment options for Lyme disease patients with lingering symptoms, Rajadas and his team began hunting for a better alternative in 2011. In 2016, they published a study in Drug Design, Development and Therapy that listed 20 chemical compounds, from about 4,000, that were most effective at killing the infection in mice. All 20 had been approved by the Food and Drug Administration for various uses. One, for instance, is used to treat alcohol abuse disorder.
Jayakumar Rajadas
In this most recent study, azlocillin, one of the top-20 contenders, was shown to eclipse a total of 7,450 compounds because it is more effective in killing B. burgdorferi and causes fewer side effects. Lyme disease affects more than 300,000 people annually, according to the Centers for Disease Control and Prevention. It can affect various organs, including the brain, skin, heart, joints and nervous system, and cause heart problems and arthritis if untreated. Symptoms include fever, headaches, chills, and muscle and joint pain.
Traditional antibiotics, such as doxycycline, are effective as an early course of treatment for the infection in the majority of patients, but it remains unclear why these drugs fail to treat 10% to 20% of patients, Rajadas said.
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What Is Post Treatment Lyme Disease
Post Treatment Lyme Disease represents a research subset of patients who remain significantly ill 6 months or more following standard antibiotic therapy for Lyme disease. PTLD is characterized by a constellation of symptoms that includes severe fatigue, musculoskeletal pain, sleep disturbance, depression, and cognitive problems such as difficulty with short-term memory, speed of thinking, or multi-tasking. In the absence of a direct diagnostic biomarker blood test, PTLD has been difficult to define by physicians, and its existence has been controversial. However, our clinical research shows that meticulous patient evaluation when used alongside appropriate diagnostic testing can reliably identify patients with a history of previously treated Lyme disease who display the typical symptom patterns of PTLD.
When Should I Call The Doctor
If a tick bites you, call your doctor. Other conditions can cause similar symptoms, so it’s always a good idea to discuss them with your doctor. That way you can get checked and treated, if needed. Call right away if you get a red-ringed rash, lasting flu-like symptoms, joint pain or a swollen joint, or facial paralysis.
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Healthy Vs Weak Cells
How all this plays out is a function of the health of cells as much as the aggressiveness of the bacteria: Cells that are weak from being chronically stressed are more vulnerable to invasion by bacteria.
A healthy person with healthy cells who is bitten by a tick may not have much in the way of acute symptoms and may never develop chronic symptoms. It doesnt mean, however, that the bacteria have been eradicated from the body. They can stay dormant in tissues for a lifetime.
All it takes is a shift in the health of cells for dormant bacteria to surface and invade more cells. The immune system scrambles to keep a lid on things as bacteria erupt and infect other cells. Dead cells break apart and create debris. Macrophages secrete acid and free radicals to break down debris. Reinforcements are called in. More acid. More free radicals. More collateral damage. More debris. Flow of nutrients and oxygen is obstructed and cells are weakened even further.
The invasion intensifies as more cells are infected. Along with inflicting injury to cells in tissues, bacteria infect and kill WBCs. In addition, bacteria throw the immune system off balance by disrupting the cytokines the immune system uses to coordinate the resistance. As the process spirals out of control, the immune system loses the capacity to keep microbes in check.
Before long, tissues throughout the body start to look like a war zone. Cells suffer. Symptoms result. It becomes a never-ending cycle of misery.
How Is Lyme Disease Treated
In its early stages, Lyme disease, an infection caused by the bacterium Borrelia burgdorferi , is most commonly treated with simple antibiotic regimens. However, at later stages, Lyme can disseminate to other parts of the body such as the brain, central nervous system, and heart and require more complex treatment programs. In addition, many of these patients are coinfected with other tick-borne pathogens, and this can affect treatment decisions. Unfortunately, diagnosing these coinfections is often very difficult and usually requires testing at a specialty laboratory that is dedicated to the detection of the ever-increasing list of pathogens associated with Lyme disease.
Currently there is no consensus among the medical and scientific communities regarding the best treatment for late-stage and chronic Lyme and associated coinfections. Uncertainties include the need for and effectiveness of long-term antibiotics and herbal remedies. Read on to learn more about the current outlook on Lyme disease treatment.
Disclaimer: IGeneX is a testing laboratory. IGeneX does not provide medical advice or endorse any particular Lyme disease treatment. If you have been diagnosed with Lyme, chronic Lyme, or another tick-borne infectious disease, it is important that you talk to a trusted physician or Lyme-literate doctor to come up with the best treatment plan for your condition and symptoms.
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Azlocillin Comes Out On Top
The drug, which is not on the market, was tested in mouse models of Lyme disease at seven-day, 14-day and 21-day intervals and found to eliminate the infection. For the first time, azlocillin was also shown to be effective in killing drug-tolerant forms of B. burgdorferi in lab dishes, indicating that it may work as a therapy for lingering symptoms of Lyme disease.
Pothineni and Rajadas have patented the compound for the treatment of Lyme disease and are working with a company to develop an oral form of the drug. Researchers plan to conduct a clinical trial.
Rajadas is also a professor of bioengineering and therapeutic sciences at the University of California-San Francisco.
Other Stanford co-authors are Hari-Hara S. K. Potula, PhD, senior research scientist postdoctoral scholars Aditya Ambati, PhD, and Venkata Mallajosyula, PhD senior research scientist Mohammed Inayathullah, PhD and intern Mohamed Sohail Ahmed.
A researcher at Loyola College in India also contributed to the work.
The study was funded by the Bay Area Lyme Foundation and Laurel STEM Fund.
- Tracie White
Hyperbaric Oxygen Therapy For Lyme Disease
Hyperbaric oxygen therapy involves exposure to 100 percent oxygen at a high pressure. Its often in a room called a hyperbaric oxygen chamber to promote wound healing.
There isnt much research about the effectiveness of hyperbaric oxygen therapy for Lyme disease. But a 2014 case study from Taiwan reports that it treated Lyme disease in a person who hadnt responded to antibiotics. Still, more large-scale studies are needed to understand whether its an effective treatment.
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Herbal And Prescription Antimicrobials By Function
Be aware the doses I provide below are for adults. These same prescriptions can be used with children but have lower doses. For pediatric dosing, talk with your family physician or pediatrician. Tetracyclines can be used in children under eight, but there is a risk of tooth staining. This staining seems not to be an issue if they are used for a month or less.
What Is The Treatment For Lyme Disease
The first-line standard of care treatment for adults with Lyme disease is doxycycline, a tetracycline antibiotic. Other antibiotics that have activity against borrelia include the penicillin-like antibiotic, amoxicillin, and the second generation cephalosporin, Ceftin. The mainstay of treatment is with oral antibiotics, but intravenous antibiotics are sometimes indicated for more difficult to treat cases of neurologic-Lyme disease, such as meningitis, and cases of late Lyme arthritis.
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Herbal & Prescription Lyme Disease Antibiotics
In this article, you will learn how to build a Lyme disease herbal or prescription antibiotic treatment. Later, in this guide I provide nine sample herbal and prescription antibiotic treatment plans, including the dosing regimens I find effective.
The focus of this article is on Lyme germ treatment. For information about treating Lyme disease coinfections see
Before I describe these plans, you should be aware that chronic Lyme disease recovery requires more than antibiotics. I cannot emphasize this point strongly enough. Treating Borrelia, the Lyme germ, with antibiotics is complicated because limited research shows which treatment regimens work best. As a result, many Lyme-Literate Medical Doctors , like me, prescribe antibiotics based on theory, in addition to our collective observation, which is that combinations of antimicrobials work better than single agents alone. It is critical that a Lyme disease treatment regimen addresses the first ten steps outlined in my Lyme disease treatment guidelines, The Ross Lyme Support Protocol. These steps are designed to revive health and to boost the immune system. Even a year or more into treatment, when a person is feeling better, these steps are essential to speed recovery by supporting the immune system.
Type Of Clinician Overseeing Care
We asked patients to tell us the type of clinician overseeing their care. Choices included: family physicians, internists, rheumatologists, infectious disease specialists, and clinicians whose practice focused on tick-borne diseases . Very few patients selected an infectious disease specialist. Seventy-five percent of high responders and well patients report having their care overseen by an LLMD.
Physicians who treat Lyme disease as their primary focus might be expected to have better results than physicians who dont simply because volume of cases handled means a greater experience level. It is commonly recognized in medicine that volume of cases is associated with better treatment outcomes . Just as patients with cancer commonly seek out physicians who specialize in that area, perhaps patients with chronic Lyme disease should also.
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Lyme Disease Natural Treatment Safety
If you decide to explore natural treatments for Lyme disease, talk to your doctor about the risks beforehand. Natural treatments, just like traditional treatments, can still be toxic or dangerous. But in combination with medical treatment, a complementary approach might improve health.
For example, a product called bismacine contains an injectable form of bismuth. This is a type of metal thats a common ingredient in some digestive aids. But bismacine contains a higher dose of bismuth thats injectable. Injecting a high dose of bismuth can cause bismuth poisoning, which can lead to heart and kidney failure.
Other natural treatments may interact with other medications or supplements you take. Your doctor can help you confirm whether any medications you currently take will interact with treatment youre interested in trying.
What Factors Determine How Patients Respond To Treatment
To find out what made some patient substantially improve or become well, we turned to our academic partners at the University of California at Los Angeles who specialize in artificial intelligence and machine learning. Their team looked at 215 features related to diagnostic factors, treatment approach, duration of individual antibiotics, alternative treatments, symptoms, type of clinician, and functional impairment to identify the 30 top predictive features for treatment response . Most of the top 30 features identified in their study related to chronic Lyme disease treatment , symptom severity , and type of clinician treating Lyme disease. We analyzed three of these factors associated with treatment response:
- Treatment approach
- Treatment durations
- Type of clinician overseeing the patients care
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What Are The Risk Factors For Post Treatment Lyme Disease
Risk factors for Post Treatment Lyme Disease include:
- Delay in diagnosis
- Increased severity of initial illness
- Presence of neurologic symptoms
Increased severity of initial illness, the presence of neurologic symptoms, and initial misdiagnosis increase the risk of Post Treatment Lyme Disease. PTLD is especially common in people that have had neurologic involvement. The rates of Post Treatment Lyme Disease after neurologic involvement may be as high as 20% or even higher. Other risk factors being investigated are genetic predispositions and immunologic variables.
In addition to Borrelia burgdorferi, the bacteria that causes Lyme disease, there are several other tick-borne co-infections that may also contribute to more prolonged and complicated illness.
How Do You Treat Lyme Disease Naturally
You can treat Lyme disease naturally with custom-made Homeopathy medicines from Welling Homeopathy Clinics. You can also treat late-stage Lyme disease and Post-Lyme disease syndrome.
Consult our specialists today for a detailed evaluation and to start your customised Homeopathy treatment of Lyme Disease.
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Natural Remedies For Lyme Disease
Lyme disease is a bacterial infection caused by the bacterium Borrelia burgdorferi. It is spread through the bite of infected ticks.
Ticks are very small, and their biteswhich can occur anywhere on the bodyare usually painless, so you may not immediately be aware that you have been bitten. In most cases, the tick must be attached to the body for 24 hours before Lyme disease is transmitted.
The signs and symptoms of Lyme disease usually start within three to 30 days after youve been bitten by an infected tick. Many people experience flu-like symptoms after being bitten, while more serious symptoms show up weeks after the bite. Early signs and symptoms of Lyme disease include:
- Chills
- Rash
- Swollen lymph nodes
If left untreated, symptoms can worsen to include Bells palsy , severe headaches, muscle, joint, and tendon pain, cardiac problems, and neurological disorders.
Most cases of Lyme disease can be managed and treated with two to three weeks of antibiotics. Depending on the severity of your symptoms and how long after the bite you were diagnosed, you may need a longer course of antibiotics to clear up the infection. Many people turn to natural remedies to help treat Lyme disease.